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An Inhalation Anesthetic Technique is Preferable for Patients Undergoing Coronary Artery Bypass Grafting

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Abstract

What is the “best” method for anesthetizing patients for coronary artery bypass graft (CABG) surgery? Is there a “best” method? The very low morbidity and mortality reported from many centers where different anesthetics are employed [1] would suggest that there is no ideal technique. Nevertheless, it appears that the reflex response of many anesthesiologists when confronted with a patient for CABG (or for that matter any patient with “severe” heart disease) is to reach for one of the potent intravenous narcotics. To give these drugs their due, the current popularity of high-dose narcotic techniques for CABG is, no doubt, based upon their safety, the “railroad track” hemodynamics [2, 3] that often accompany their administration, and their ease of use. In many centers, volatile anesthetics have been relegated to the occasional role of treating a bit of hypertension here and there. We feel this is simplistic, inappropriate, makes little use of the beneficial properties of the vapors, and is incredibly boring. Therefore the aim of this chapter is to discuss the rationale for selecting a volatile agent as the primary anesthetic for CABG patients. We hope to encourage the intelligent use of volatile drugs by describing their safety and efficacy in patients with coronary artery disease as well as delineating potential problems or difficulties with their use.

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References

  1. Miller DC, Stinson EB, Oyer PE, et al.: Discriminant analysis of the changing risks of coronary artery operations: 1971–1979. J Thorac Cardiovasc Surg 85:197, 1983.

    PubMed  CAS  Google Scholar 

  2. Delange S, Boscoe MJ, Stanley TH: Comparison of sufentanil-O2 and fentanyl-O2 for coronary artery surgery. Anesthesiology 56:112, 1982.

    Article  CAS  Google Scholar 

  3. Stanley TH, Webster LR: Anesthetic requirements and cardiovascular effects of fentanyl-O2 and fentanyl-diazepam-O2 anesthesia in man. Anesth Analg 57:411, 1978.

    PubMed  CAS  Google Scholar 

  4. Slogoff S, Keats AS: Does perioperative myocardial ischemia lead to postoperative myocardial infarction? Anesthesiology 62:107, 1985.

    Article  PubMed  CAS  Google Scholar 

  5. Slogoff S, Keats AS: Further observations on perioperative myocardial ischemia. Anesthesiology 65:539, 1986.

    Article  PubMed  CAS  Google Scholar 

  6. Isom OW, Spencer FC, Feigenbaum H, Cunningham Jn Jr, Roe C: Prebypass myocardial damage in patients undergoing coronary revascularization: an unrecognized vulnerable period. Circulation [Suppl] 52:11–119, 1975.

    Google Scholar 

  7. Merin, RG, Lowenstein E, Gelman S: Is anesthesia beneficial for the ischemic heart? III. Anesthesiology 64:137, 1986.

    Article  PubMed  CAS  Google Scholar 

  8. Bland JHL, Lowenstein E: Halothane induced decrease in experimental myocardial ischemia in the non-failing canine heart. Anesthesiology 45:287, 1976.

    Article  PubMed  CAS  Google Scholar 

  9. Roizen MF, Hamilton WK, Yung JS: Treatment of stress-induced increases in pulmonary capillary wedge pressure using volatile anesthetics. Anesthesiology 55:446–450, 1981.

    Article  PubMed  CAS  Google Scholar 

  10. Dole WP, Alexander GM, Campbell AB, Hixson EL, Bishop VS: Interpretation and physiological significance of diastolic coronary artery pressure-flow relationships in the canine coronary bed. Cir Res 55:215–226, 1984.

    CAS  Google Scholar 

  11. Lowenstein E, Foex P, Francis CM, Davies WL, Yusuf S, Ryder WA: Regional ischemic ventricular dysfunction in myocardium supplied by a narrowed coronary artery with increasing halothane concentration in the dog. Anesthesiology 55:349, 1981.

    Article  PubMed  CAS  Google Scholar 

  12. Behrenbeck T, Nugent M, Quasha A, Hoffman E, Ritman E, Tinker J: Halothane and ischemic regional myocardial wall dynamics. Anesthesiology 53:5140, 1980.

    Article  Google Scholar 

  13. Buffington CW: Impaired systolic thickening associated with halothane in the presence of a coronary stenosis is mediated by changes in hemodynamics. Anesthesiology 64:632, 1986.

    Article  PubMed  CAS  Google Scholar 

  14. Verrier ED, Edelist G, Consigny PM, Robinson S, Hotfman JIE: Greater coronary vascular reserve in dogs anestheticed with halothane. Anesthesiology 53:445–459, 1980.

    Article  PubMed  CAS  Google Scholar 

  15. Merin RG: Are the myocardial functional and metabolic effects of isoflurane really different from those of halothane and enflurane? Anesthesiology 55:398, 1981.

    Article  PubMed  CAS  Google Scholar 

  16. Sonntag H, Larsen R, Hilfiker O, Kettler D, Brockschnieder B: Myocardial blood flow and oxygen consumption during high dose fentanyl anesthesia in patients with coronary artery disease. Anesthesiology 56:417, 1982.

    Article  PubMed  CAS  Google Scholar 

  17. Moffit EA, Scovil JE, Barker RA: Myocardial metabolism and hemodynamic response during high dose fentanyl anesthesia for coronary patients. Can Anaesth Soc J 31:611, 1984.

    Article  PubMed  CAS  Google Scholar 

  18. Rao TLK, Jacobs KH, El-Etr AA: Reinfarction following anesthesia in patients with myocardial infarction. Anesthesiology 58:499–505, 1983.

    Article  Google Scholar 

  19. Moffitt EA, Sethna DH: The coronary circulation and myocardial oxygenation in coronary artery disease: effects of anesthesia. Anesth Analg 65:395, 1986.

    PubMed  CAS  Google Scholar 

  20. Moffitt EA, Sethna DH, Bussell JA, Raymond M, Matloff JM, Gray RJ: Myocardial metabolism and hemodynamic responses to halothane or morphine anesthesia for coronary artery surgery. Anesth Analg 61:979, 1982.

    Article  PubMed  CAS  Google Scholar 

  21. Reiz S, Balfors E, Gustavsson B, Haggmark S, Nath S, Rydvall A, Truedsson H: Effects of halothane on coronary hemodynamics and ischemic heart disease and heart failure. Acta Anaesthesiol Scand 26:133, 1982.

    Article  PubMed  CAS  Google Scholar 

  22. Delaney TJ, Kistner JR, Lake CL, Miller ED: Myocardial function during halothane and enflurane anesthesia in patients with coronary artery disease. Anesth Analg 59:240, 1980.

    PubMed  CAS  Google Scholar 

  23. Moffit EA, Imrie DD, Scovil JE, Glenn JJ, Couisins CL, DelCampo C, Sullivan JA, Kinley CE: Myocardial metabolism and haemodynamic responses with enflurane anesthesia for coronary artery surgery. Can Anaesth Soc J 31:604, 1984.

    Article  Google Scholar 

  24. Rydvall A, Haggmark S, Nyhman H, Reiz S: Effects of enflurane on coronary hemodynamics in patients with ischemic heart disease. Acta Anaesthesiol Scand 28:690, 1984.

    Article  PubMed  CAS  Google Scholar 

  25. Eger II EI: Isoflurane: a review. Anesthesiology 55:559, 1981.

    Article  PubMed  Google Scholar 

  26. Gelman S, Fowler KC, Smith LR: Regional blood flow during isoflurane and halothane anesthesia. Acta Anaesthesiol Scand 63:557, 1984.

    CAS  Google Scholar 

  27. Reiz S, Balfors E, Sorensen MB, Ariola S, Friedman A, Truedsson H: Isoflurane: a powerful coronary vasodilator in patients with coronary artery disease. Anesthesiology 59:91, 1983.

    Article  PubMed  CAS  Google Scholar 

  28. Moffit EA, Barker RA, Glenn JJ, Imrie DD, Delcampo C, Landymore RW, Kinley CE, Murphy DP: Myocardial metabolism and hemodynamic responses with isoflurane anesthesia for coronary arterial surgery. Anesth Analg 65:53, 1986.

    Google Scholar 

  29. Larsen R, Hilfiker O, Merkel G, Sonntag H, Drobnik L: Myocardial oxygen balance during enflurane and isoflurane anesthesia for coronary artery surgery [abstr]. Anesthesiology 61: A4, 1984.

    Article  Google Scholar 

  30. Tarnow J, Markschies-Horning A, Schulte-Sasse V: Isoflurane increases the tolerance to pacing induced myocardial ischemia. Anesthesiology 64:147, 1986.

    Article  PubMed  CAS  Google Scholar 

  31. Smith JS, Cahalan MK, Benefiel DJ, Lurz FW, Lampe GH, Byrd BJ, Schiller NB, Yee ES, Turley K, Ullyot DJ, Hamilton WR: Fentanyl versus fentanyl-isoflurane in patients with impaired left ventricular function, [abstr]. Anesthesiology 63:A3, 1985.

    Article  Google Scholar 

  32. Buffington CW, Romson JL, Leven A, Duttlinger NC, Huang AW: Isoflurane induces coronary steal in a canine model of chronic coronary occlusion. Anesthesiology 66:280, 1987.

    Article  PubMed  CAS  Google Scholar 

  33. Sill JC, Bove AA, Nugent M, Blaise GA, Dewey JD, Griban C: Effects of isoflurane on coronary arteries and coronary arterioles in the dog. Anesthesiology 66:262, 1987.

    Article  Google Scholar 

  34. Becker LC: Is isoflurane dangerous for the patient with coronary artery disease? Anesthesiology 66:259, 1987.

    Article  PubMed  CAS  Google Scholar 

  35. Lichtenthal PR, Wade LD, Niemyski R, Shapiro BA: Respiratory management after cardiac surgery with inhalation anesthesia. Crit Care Med 11:603, 1983.

    Article  PubMed  CAS  Google Scholar 

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© 1988 Kluwer Academic Publishers, Boston

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Kramer, J.L., Wagner, D.J., Thomas, S.J. (1988). An Inhalation Anesthetic Technique is Preferable for Patients Undergoing Coronary Artery Bypass Grafting. In: Fyman, P.N., Gotta, A.W. (eds) Controversies in Cardiovascular Anesthesia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1771-5_1

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  • DOI: https://doi.org/10.1007/978-1-4613-1771-5_1

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8993-7

  • Online ISBN: 978-1-4613-1771-5

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