Abstract
The continuing development of ablative procedures for tachyarrhythmia control has directed research efforts towards evaluating different types of ablative energies in an effort to find the optimal physical technique [1–4]. Recently, the use of laser energy for myocardial ablation has been extensively examined in experimental studies, and this has led to clinical application of this technique [3–20]. The experimental basis for the clinical technique has been under study in our laboratory since 1984 and has resulted in clinical application in patients with malignant supraventricular and ventricular tachycardias. The clinical efficacy and safety of the laser ablation technique is now being evaluated for intraoperative and transcatheter myocardial ablation. The technique itself is influenced by three variables, namely, the physical aspects of the laser energy source, the energy delivery technique and medium, and the myocardial substrate for ablation [21]. While our experimental studies have examined a variety of issues relating to all of these variables, current clinical trials will need to establish the methodology, efficacy, and safety of the technique in the clinical arena.
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© 1988 Martinus Nijhoff Publishing, Boston
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Saksena, S. (1988). Histologic Effects of Laser-Induced Myocardial Damage. In: Scheinman, M.M. (eds) Catheter Ablation of Cardiac Arrhythmias. Developments in Cardiovascular Medicine, vol 78. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1765-4_6
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DOI: https://doi.org/10.1007/978-1-4613-1765-4_6
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