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Production of Clotting Factors Through Biotechnology

  • L.-O. Andersson
Chapter
Part of the Developments in Hematology and Immunology book series (DIHI, volume 21)

Abstract

Fractionation of plasma is a way to prepare a number of proteins for clinical use, of great value in treatment and prevention of a number of diseases and disease states. Of special importance are the coagulation factor concentrates used for treatment of hemophilia. In treatment of hemophilia A Factor VIII concentrates are used and for treatment of hemophilia B Factor IX concentrates. Before those concentrates were developed there was essentially no treatment for hemophilia patients and life-expectancy was poor. Average lifespan was around 16 years. With the introduction of the Factor VIII and IX concentrates in the 60ties life has completely changed for hemophilia patients. They now can live an almost normal life.

Keywords

Factor VIII Hemophilia Patient Factor Viii Gene Human Factor VIII Plasma Factor VIII 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers, Boston 1988

Authors and Affiliations

  • L.-O. Andersson

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