The Role of Diet in the Etiology and Causation of Breast Cancer
Common diseases have common causes. Since 1 out of 10 women will develop breast cancer in their lifetime, the disease must have a common cause. In investigating the etiology of breast cancer, we need to determine the relative contribution made by such generally established risk factors as age of first pregnancy, late menopause, nulliparity, family history, and less well established risk factors as obesity, long-term lactation and fibrocystic disease. We believe that these risk factors cannot explain the reported differences in incidence between the United States and Japan, countries with major differences in the rates of pre- and particularly postmenopausal breast cancer. If these factors account for only a portion of the observed differences, then we need to examine other variables, that are both common and could account, at least in part, for these differences. One such factor is likely to be the consumption of dietary fat.
KeywordsCholesterol Obesity Corn Estrogen Adenocarcinoma
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