Vaccinia virus oncolysates in the treatment of malignant melanoma

  • Jerry A. Bash
  • Marc K. Wallack
Part of the Cancer Treatment and Research book series (CTAR, volume 43)

Abstract

Melanoma is undoubtedly the most extensively studied human malignancy from the standpoint of both immunobiological analysis of the tumor and immunotherapeutic approaches to the disease [1–4]. The reasons for this degree of immunological interest in melanoma include (1) the frequency of spontaneous regressions, which are felt to involve host immune mechanisms [5]; (2) the prognostic significance of lymphoid infiltration of lesions [6]; (3) the demonstration of both antibody and cell-mediated antimelanoma responses in untreated melanoma patients [7]; and (4) the plethora of melanoma-associated antigens that have been documented [8, 9].

Keywords

Influenza Radionuclide Sarcoma Cyclophosphamide Ferritin 

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Copyright information

© Kluwer Academic Publishers, Boston 1988

Authors and Affiliations

  • Jerry A. Bash
  • Marc K. Wallack

There are no affiliations available

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