Silent Myocardial Ischemia and Sudden Cardiac Death

  • Leonard N. Horowitz
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 88)


Coronary artery disease is the major cause of death in Western society and the mechanism of death is usually a malignant ventricular arrhythmia. These arrhythmias commonly cause sudden cardiac death and in fact the initial clinical manifestation of coronary artery disease is sudden cardiac death in a substantial number of patients. These malignant ventricular arrhythmias may result from one or more of several mechanisms. They may be caused by scarring and an electrophysiologic-anatomic melieu which allows the initiation of sustained ventricular arrhythmias or acute myocardial infarction. Recently, interest has been growing in the study of silent myocardial ischemia and its role in sudden cardiac death. This chapter reviews the relationship between silent myocardial ischemia and sudden cardiac death.


Cardiac Arrest Myocardial Ischemia Sudden Cardiac Death Ventricular Fibrillation Ventricular Tachyarrhythmia 
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Copyright information

© Kluwer Academic Publishers, Boston 1988

Authors and Affiliations

  • Leonard N. Horowitz
    • 1
  1. 1.Philadelphia Heart InstitutePresbyterian-University of Pennsylvania Medical CenterPhiladelphiaUSA

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