Experimental Pancreas Transplantation

  • Luis H. Toledo-Pereyra


Experimental work in the field of pancreas transplantation has been hindered by the small number of animal models with naturally occurring diabetes mellitus. As a result, the diabetic state must therefore be induced either pharmacologically, with streptozotocin or alloxan, or surgically by means of pancreatectomy. In addition, it has become quite difficult to differentiate between technical and immunological problems, especially because allograft models are so commonly used. Nevertheless, substantial information in the field of experimental pancreas transplantation has been produced regarding surgical techniques, preservation, the management of exocrine secretions, rejection, and immunosuppression.


Pancreatic Duct Transplant Proc Pancreas Transplantation Total Lymphoid Irradiation Pancreatic Graft 
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© Kluwer Academic Publishers 1988

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  • Luis H. Toledo-Pereyra

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