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Experimental Pancreas Transplantation

  • Luis H. Toledo-Pereyra

Abstract

Experimental work in the field of pancreas transplantation has been hindered by the small number of animal models with naturally occurring diabetes mellitus. As a result, the diabetic state must therefore be induced either pharmacologically, with streptozotocin or alloxan, or surgically by means of pancreatectomy. In addition, it has become quite difficult to differentiate between technical and immunological problems, especially because allograft models are so commonly used. Nevertheless, substantial information in the field of experimental pancreas transplantation has been produced regarding surgical techniques, preservation, the management of exocrine secretions, rejection, and immunosuppression.

Keywords

Pancreatic Duct Transplant Proc Pancreas Transplantation Total Lymphoid Irradiation Pancreatic Graft 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Kluwer Academic Publishers 1988

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  • Luis H. Toledo-Pereyra

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