Abstract
Nowhere in the management of prostate cancer is there more controversy than in dealing with incidental, latent, or localized disease. We would anticipate that the widespread use of fine needle aspiration, perhaps combined with ultrasound, will introduce a previously unstudied population and thus compound the uncertainties about the clinical approach to early prostate cancer. It is not surprising that there is little uniformity of opinion about the clinical management of such patients since there is very substantial divergence of opinion and uncertainty about the very definition of what constitutes the origins and natural history of incipient carcinoma of the prostate. Current concepts of the early biology of prostate cancer are based more on inference and conjecture than upon objective clinico-pathologic documentation.
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© 1988 Plenum Press, New York
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Gardner, W.A., Culberson, D.E. (1988). The Proto-Biology of Prostate Cancer. In: Coffey, D.S., Resnick, M.I., Dorr, F.A., Karr, J.P. (eds) A Multidisciplinary Analysis of Controversies in the Management of Prostate Cancer. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1667-1_5
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DOI: https://doi.org/10.1007/978-1-4613-1667-1_5
Publisher Name: Springer, Boston, MA
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