Abstract
The ideal screening test for early detection of carcinoma of the prostate would be non-invasive and preferable could be performed on readily available biological fluids, e.g., serum, urine, prostatic fluid. When considering an ideal test it is also important to study it in a correct statistical manner and not only calculate the sensitivity and specificity of the study but also the positive and negative predictive values. These terms will be discussed in more detail in the following paragraphs. Finally, progressive or potentially progressive disease must be identified and differentiated from non-progressive or non-lethal disease. Obviously patients in the former category would be treated differently than those in the latter group.
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References
Watson, R.A. and Tang, D.B. The predictive value of prostaticacid phosphatase as a screening test for prostatic cancer. New Engl. J. Med. 303:497–499, 1980.
Vecchio, T.J. Predictive value of a single diagnostic test in munselected populations. New Engl. J. Med. 274:1171–1173, 1966.
Sheps, S.B. and Schecter, M.T. The assessment of diagnostictests. A survey of current medical research. JAMA 252:2418–2422, 1984.
Barnes, R.W. Carcinoma of the prostate: a comparative study of mode of treatment. J. Urol. 44:169–176, 1940.
Kimbrough, J.C. and Rowe, R.B. Carcinoma of the prostate. J. Urol. 66:373–378, 1951.
Jewett, H.J. Significance of the palpable prostatic nodule. JAMA 160:838–839, 1950.
Grabstald, H. Further experience with transrectal biopsy of the Prostate. J. Urol. 74:211–22, 1955.
Vihko, P., Kontturi, M., Lukkarinen, O., Errasti, J. and Vihko, R. Screening for carcinoma of the prostate. Rectal examination and enzymatic and radioimmunologic measurements of serum acid Pphosphatase compared. Cancer 56:173–177, 1985.
Chodak, G.W. and Schoenberg, H.W. Early detection of prostate cancer by routine screening. JAMA 252:3261–3264, 1984.
Letters to the Editor. Problematic prostatic prediction. JAMA 254:1171–1173, 1984.
Thompson, I.M., Ernst, J.J., Gangai, M.P. and Spense, C.R. Adenocarcinoma of the prostate: results of routine urological screening. J. Urol. 132:690–692, 1984.
Guinan, P., Bush, I., Ray, J., Vieth, R., Rao, R. and Bratti, R. The accuracy of the rectal examination in the diagnosis of prostate carcinoma. New Engl. J. Med. 303:499–503, 1980.
Bartsch, G., Egender, G., Hubscher, H. and Rohr, H. Sonometries of the prostate. J. Urol. 127:1119–1121, 1982.
Holm, H.H., Juul, N., Pedersen, J.F., Hansen, H. and Stroyer, I. Transperineal 125 iodine seed implantation in prostatic cancer guided by transrectal ultrasonography. J. Urol. 130:283–286, 1983.
Pontes, J.E., Eisenkraft, S., Watanabe, H., Ohe, M., Saitoh, M. and Murphy, G.P. Preoperative evaluation of localized prostatic carcinoma by transrectal ultrasonography. J. Urol. 134:289–291, 1985.
Watanabe, H., Ohe, H., Inabe, T., Itakura, Y., Saitoh, M. and Nakao, M. A mobile mass screening unit for prostatic disease. The Prostate 5:559–565, 1984.
Resnick, M.I. Use of transrectal ultrasound in evaluating prostatic cancer. J. Urol. 134:314, 1985.
Resnick, M.I. Evaluation of prostatic carcinoma: noninvasive and preoperative techniques. The Prostate 1:311–320, 1980.
Rifkin, M.D., Friedland, G.W. and Shortliffe, L. Prostatic evaluation by transrectal endosonography: detection of carcinoma. Radiology 158:85–90, 1986.
Lee, F., Gray, J.M., McLeary, R.D., Lee, F., Jr, McHugh, T.A., Solomon, M.H., Kumasaka, G.H., Straub, W.H., Borlaza, G.S. and Murphy, G.P. Prostatic evaluation by transrectal sonography: criteria for diagnosis of early carcinoma. Radiology 158:91–95, 1986.
Foti, A.G., Cooper, J.F., Herschman, H. and Malvaez, R.R. Detection of prostatic cancer by solid-phase radioimmunoassay of serum prostatic acid phosphatase. New Engl. J. Med. 297:1357–1361, 1977.
Carroll, B.J. Radioimmunoassay of prostatic acid phosphatase in carcinoma of the prostate. New Engl. J. Med. 298:912, 1978.
Fleischmann, J., Catalona, W.J., Fair, W.R., Heston, W.D.W. and Menon, M. Lack of value of radioimmunoassay for prostatic acid phosphatase as a screening test for prostatic cancer in patients with obstructive prostatic hyperplasia. J. Urol. 129:312–314, 1983.
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© 1988 Plenum Press, New York
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Resnick, M.I. (1988). Approaches to Discovering More Effective Treatments for Prostate Cancer Early Diagnosis and Screening. In: Coffey, D.S., Resnick, M.I., Dorr, F.A., Karr, J.P. (eds) A Multidisciplinary Analysis of Controversies in the Management of Prostate Cancer. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1667-1_25
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DOI: https://doi.org/10.1007/978-1-4613-1667-1_25
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