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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 228))

Abstract

More than ninety years ago, Stillmark (1888) discovered that castor-bean extracts caused agglutination of human red cells. Boyd and Shapeleigh (1954) invented the term “lectin” (from legere, to select) for this group of plant proteins which are capable of hemagglutination. It soon became apparent that lectins are carbohydrate-binding proteins. Modern nomenclature defines lectins as carbohydrate-binding proteins which are not immunoglobulins or enzymes.

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References

  • Achord, D., Brot, F., and Sly, W. (1977). “Inhibition of the ratclearance system for agalacto-orosomucoid by yeast mannan and by mannose.” Biochem. Biophys. Res, Commun. 77:409–415.

    Article  CAS  Google Scholar 

  • Ashwell, G. and Harford, J. (1982). “Carbohydrate-specific receptors of the liver.” Ann. Rev. Biochem. 51:531–554.

    Article  PubMed  CAS  Google Scholar 

  • Ashwell, G. and Morell, A. (1974). “The role of surface carbohydrates in the hapatic recognition and transport of circulating glycoproteins.” Adv. Enzymol. Relat. Areas Mol. Biol. 41:99–128.

    PubMed  CAS  Google Scholar 

  • Barondes, S.H. (1984). “Soluble lectins: a new class of extracellular proteins.” Science 223:1259–1264.

    Article  PubMed  CAS  Google Scholar 

  • Baynes, J., and Mold, F. (1976). “Effect of glycosylation on the in vivo circulating half-life of ribonuclease.” J. Biol. Chem. 261: 6016–6124.

    Google Scholar 

  • Bodmer, J. L. and Dean, R. T. (1983). “Does the induction of macrophage lysosomal enzyme secretion by zymosan involve the mannose receptor?” Biochem. Biophys. Res. Commun. 113, 192–198.

    Article  PubMed  CAS  Google Scholar 

  • Boyd, W. Co and Shapeleigh, E. (1954). “Specific precipitating activity of plant agglutinins (Lectins).” Science 119:419.

    Article  PubMed  CAS  Google Scholar 

  • Brownell, M. D., Colley, K. J., and Baenziger, J. U. (1984). “Synthesis, processing, and secretion of the core-specific lectin by rat hepatocytes and hepatpoma cells.” J. Biol. Chem. 259:3925–3932.

    PubMed  CAS  Google Scholar 

  • Colley, K. J. and Baenziger, J. U. (1985). “Relationship of post-translational modification to complex assembly and secretion of the rat core-specific lectin.” Proc. VIIIth Interntl. Symp. on Glycoconjugates (Houston, TX), Praeger, NY, p„ 353.

    Google Scholar 

  • Doebber, T. W., Wu, M. S., Bugianess, R. L., Ponpipom, M. M„, Furbish, F. S., Barranger, J9J Brady, R.O., and Shen, T. Y. (1982). “Enhanced macrophage uptake of synthetically glycosylated human placenatal p-glucoscerebrosidase.” J. Biol. Chem. 257:2193–2199.

    PubMed  CAS  Google Scholar 

  • Hoppe, C. A. and Lee, Y. C. (1982). “Stimulation of mannose-binding activity in the rabbit alveolar macrophage by simple sugars.” J. Biol. Chem. 257:12831–12834.

    PubMed  CAS  Google Scholar 

  • Hoppe, C. A. and Lee, Y. C. (1983). “The binding and processing of mannose-binding serum albumin derivatives by rabbit alveolar macrophages.” J. Biol. Chem. 258;14193–14199.

    PubMed  CAS  Google Scholar 

  • Kawasaki, T. (1979). “Mannan-bind ing protein — a receptor for lysosomal enzymes.” Seikagaku, 51;447–451.

    PubMed  CAS  Google Scholar 

  • Kawasaki, T., Etoh, R., and Yamashina, I. (1978). “Isolation and char ac ter i z at ion of a mannan-binding protein from rabbit liver.” Biochem. Biophys. Res. Commun. 81:1018–1024.

    Article  PubMed  CAS  Google Scholar 

  • Kawasaki, N., Kawasaki, T., and Yamashina, I. (1983). “Isolation and characterication of mannan-binding protein from human serum.” J. Biochem. (Tokyo) 94:937–947.

    CAS  Google Scholar 

  • Kawasaki, T., Mizuno, Y., Masuda, T., and Yamashina, I. (1980). “Mannan-binding protein in lymphoid tissues of rats.” J. Biochem. (Tokyo) 88:1891–1894.

    CAS  Google Scholar 

  • Kawasaki, T., Mori, K., Oka, S., Ikeda, K., and Yamashina, I (1985) Proc. VIIIth Internatl. Symposium on Glycoconjugates, (Houston, TX), Praeger, N.Y., p.146.

    Google Scholar 

  • Kozutsumi, Y., Kawasaki, T., and Yamashina, I. (1980). “Isolation and characterization of a mannan-binding protein from rabbit serum.” Biochem. Biophys. Res. Commun. 95:658–664.

    Article  PubMed  CAS  Google Scholar 

  • Kuhlenschmidt, T. and Lee, Y. C. (1982). “Isolation of a mannose- binding protein from chicken serum.” Fed. Proc. 41:1033.

    Google Scholar 

  • Kuhlenschmidt, T. and Lee, Y. C. (1984). “Specificity of chicken liver carbohydrate binding protein.” Biochemistry 23:3569–3575.

    Article  PubMed  CAS  Google Scholar 

  • Kuhlenschmidt, T., Kuhlenschmidt, M., Roseman, S., and Lee, Y. C. (1984) Biochemistry 23:437–6444.

    Google Scholar 

  • Largent, B. L., Walton, K. M., Hoppe, C. A., Lee, Y. C., and Schnaar, R. L. (1984). “Carbohydrate-specific adhesion of alveolar macrophages to mannose-derivatized surfaces.” J. Biol. Chem. 259:1764–1769.

    PubMed  CAS  Google Scholar 

  • Lee, R.T. and Lee, Y.C. (1982). “Neoglycoprote ins as probes for binding and cellular uptake of glycoconjugates.” in “The Glycoconjugates”, Vol. 4 (Ed. M. Horowitz), Acad. Press, N.Y., p.57–83.

    Google Scholar 

  • Loeken, M. R. and Roth, T. F. (1983). “Analysis of maternal I subpopulations which are transported into the chicken oocyte.” Immunology 49:21–28.

    PubMed  CAS  Google Scholar 

  • Maynard, Y. and Baenziger, J. U. (1981). “Oligosaccharide-specific endocytosis by isolated rate hepatic reticuloendothelial cells.” J. Biol. Chem. 256:8063–8068.

    PubMed  CAS  Google Scholar 

  • Mizuno, Y., Kozutsumi, Y., Kawasaki, T., Yamashina, I. (1981). Isolation and characterization of a mannan-binding protein from rat liver.” J. Biol. Chem. 256:4247–4252.

    PubMed  CAS  Google Scholar 

  • Mori, K., Kawasaki, T., Yamashina, I. (1983). “Identification of the mannan-binding protein from rat livers as a hepatocyte protein distinct from the mannan receptor on sinusoidal cells.” Arch. Biochem. Biophys. 222:542–552.

    Article  PubMed  CAS  Google Scholar 

  • Oka, S., Kawasaki, T., and Yamashina, I. (1985). “Isolation and characterization of mannan-binding proteins from chicken liver.” Arch. Biochem. Biophys. 241;95–105.

    Article  PubMed  CAS  Google Scholar 

  • Pless, D.D., Lee, Y.C., Roseman, S., and Schnaar, R.L. (1983). “Specific cell adhesion to immobilized glycoproteins demonstrated using new reagents for protein and glycoprotein immobilization.” J. Chem. 258:2340–2349.

    CAS  Google Scholar 

  • Ponpipom, M. M., Bugianesi, R. L., Robbins, J. C., Doebber, T. W., and Shen, T.Y. (1981). “Cell-specific ligands for selective drug delivery to tissues and organs.” J. Med. Chem. 24:1388–1395.

    Article  PubMed  CAS  Google Scholar 

  • Riches, D. W., Watkins, J. L., and Stanworth, D. R. (1983). “Biochemical differences in the mechanism of macrophage lysosomal exocytosis initiated by zymosan particles and weak bases.” Biochem. J. 212: 869–874.

    PubMed  CAS  Google Scholar 

  • Roche, A. C., Midoux, P., Mayer, R., and Monsigny, M. (1985). “Activation of murine macrophages and human monocytes by membrane lectin-mediated endocytosis of activators-bound to neoglyco- proteins.” Proc. VIIIth International Symposium on Glycoconjugates, Houston, TX, Praeger, N.Y., p.569.

    Google Scholar 

  • Schlesinger, P. H., Rodman, J. S., Doebber, T. W., Stahl, P., Lee, Y. C., Stowell, C. P., and Kuhlenshmidt, T. (1980). “The role of extra-hepatic tissues in the receptor-mediated plasma of glycoproteins terminated by mannose or N-acetylglucosamine.” Proc. Natl. Acad. Sci. U.S.A. 192:597–606.

    CAS  Google Scholar 

  • Shepherd, V. L., Lee, Y. C., Schlesinger, P. H., and Stahl, P. D. (1981). “L-Fucose-terminated glycoconjugates are recognized by pinocytosis receptors on macrophages.” Proc. Natl. Acad. Sci. (USA) 78:1019–1022.

    Article  CAS  Google Scholar 

  • Sly, W.S. and Fischer, H.D. (1982). “The phosphomannosyl recognition system for intracellular and intercellular transport of lysosomal enzymes.” J. Cell. Biochem. 18:67–85.

    Article  PubMed  CAS  Google Scholar 

  • Stahl, P., Six, H., Rodman, J. S., Schlesinger, P., Tulsiani, D. R. P., and Touster, O. (1976). “Evidence for specific recognition sites mediating clearance of lysosomal enzymes in vivo.” Proc. Natl. Acad. Sci. U.S.A. 73:4045.

    Article  PubMed  CAS  Google Scholar 

  • Stahl, P., Rodman, J. S., Miller, M. J., and Schlesinger, P. H. (1978). “Evidence for receptor-mediated binding of glycoproteins, glycoconjugates, and lysosomal glycosidases by alveolar macrophages.” Proc. Natl. Acad. Sci U.S.A. 73:1399–1403.

    Article  Google Scholar 

  • Stillmark, H. (1888) Inaug. Diss., Dorpat., as cited in Goldstein and Hayes (1978).

    Google Scholar 

  • Sung, S.J., Nelson, R.S., and Silverstein, S.C. (1983). “Yeast mannans inhibit binding and phagocytosis of zymosan by mouse peritoneal macrophages.” J. Cell. Biol. 96:160–166.

    Article  PubMed  CAS  Google Scholar 

  • Tietze, C., Schlesinger, P. H., and Stahl, P. (1980). Chloroquine and ammonium ion inhibit receptor-mediated endocytosis of mannose- glycoconjugates by macrophages: apparent inhibition of receptor recycling.” Biochem. Biophys. Res. Commun. 93:1–8.

    Article  CAS  Google Scholar 

  • Tietze, C., Schlesinger, P. H., and Stahl, P. (1982). “Mannose-specific endocytosis receptor of alveolar macrophages: Demonstration of two functionally distinct intracellular pools of receptor and their roles in receptor recycling.” J. Cell Biol. 92:417–424.

    Article  PubMed  CAS  Google Scholar 

  • Tolleshaug, H., Berg, T., and Blomhoff, R. (1984). “Uptake of mannose- termmateci giycoprdteins in isolated rat river cells. Evidence for receptor-mediated endocytosis in hepatocytes.” Biochem. J. 223: 151–160.

    PubMed  CAS  Google Scholar 

  • Townsend, R. and Stahl, P. (1981). Isolation and characterization of a mannose/N-acetylglucosamine/fucose-binding protein from rat liver.” Biochem. J. 194:209–214.

    PubMed  CAS  Google Scholar 

  • Wang, K. Y., Kuhlenschmidt, T. B., and Lee, Y. C. (1985). “Isolation and characterization of the major mannose-binding protein in chicken serum.”

    Google Scholar 

  • Warr, G. (1980). “A macrophage receptor for (mannose/glucosamine)- glycoproteins of potential importance in phagoytic activity.” Biochem. Biophys. Res. Commun. 93:737–745.

    Article  PubMed  CAS  Google Scholar 

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© 1988 Plenum Press, New York

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Lee, Y.C. (1988). Mannose-Binding Proteins of Animal Origin. In: Wu, A.M., Adams, L.G. (eds) The Molecular Immunology of Complex Carbohydrates. Advances in Experimental Medicine and Biology, vol 228. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1663-3_5

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  • DOI: https://doi.org/10.1007/978-1-4613-1663-3_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8923-4

  • Online ISBN: 978-1-4613-1663-3

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