Retrogasserian Glycerol Injection with or without Radiofrequency Electrocoagulation for Trigeminal Neuralgia

  • Ronald Brisman
Part of the Topics in Neurosurgery book series (TINS, volume 3)

Abstract

Percutaneous retrogasserian injection of pure sterile glycerol into the trigeminal cistern may relieve the pain of trigeminal neuralgia without major complications [1–3]. In the initial reports, there was little numbness and major dysesthesias were rare [1, 2]. As further experience developed, it became apparent that glycerol is a denervating agent and that it could cause analgesia with bothersome dysesthesias [3–5]. Larger doses of glycerol (more than 0.25 ml) are likely to cause more denervation and dysesthesias than smaller doses.

Keywords

Glycerol Dust Tantalum Keratitis Sten 

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References

  1. 1.
    Hakanson S: Trigeminal neuralgia treated by the injection of glycerol into the trigeminal cistern. Neurosurgery 9:638–646, 1981.PubMedCrossRefGoogle Scholar
  2. 2.
    Lunsford LD: Treatment of tic douloureux by percutaneous retrogasserian glycerol injection. JAMA 248:449–453, 1982.PubMedCrossRefGoogle Scholar
  3. 3.
    Sweet WH, Poletti CE, Macon JB: Treatment of trigeminal neuralgia and other facial pains by retrogasserian injection of glycerol. Neurosurgery 9:647–653, 1981.PubMedCrossRefGoogle Scholar
  4. 4.
    Sweet WH: Current concepts. The treatment of trigeminal neuralgia (tic douloureux). N Engl J Med 315:174–177, 1986.PubMedCrossRefGoogle Scholar
  5. 5.
    Sweet WH, Poletti CE: Problems with retrogasserian glycerol in the treatment of trigeminal neuralgia. Appl Neurophysiol 48:252–257, 1985.PubMedGoogle Scholar
  6. 6.
    Hakanson, Sten: Retrogasserian glycerol injection as a treatment of tic douloureux. Adv Pain Res Ther 5:927–933, 1983.Google Scholar
  7. 7.
    Brisman R: Treatment of trigeminal neuralgia: Radiofrequency electrocoagulation with/ without glycerol. Contempor Neurosurg 8(3):l-5, 1986.Google Scholar
  8. 8.
    Menzel J, Piotrowski W, Penzholz H: Long-term results of Gasserian ganglion electrocoagulation. J Neurosurg 42:140–143, 1975.PubMedCrossRefGoogle Scholar
  9. 9.
    Lunsford LD, Bennett MH: Percutaneous retrogasserian glycerol rhizotomy for tic douloureux: Part 1. Technique and results in 112 patients. Neurosurgery 14:424–430, 1984.PubMedCrossRefGoogle Scholar
  10. 10.
    Brisman R: Bilateral trigeminal neuralgia. J Neurosurg 67:44–48, 1987.PubMedCrossRefGoogle Scholar
  11. 11.
    Tew JM, Tobler WD: Percutaneous rhizotomy in the treatment of intractable facial pain (trigeminal, glossopharyngeal, and vagal nerves). In: Operative Neurosurgical Techniques, Vol. 2, Schmidek HH, Sweet WH, eds. Grune & Stratton, New York, 1982, pp 1083–1106.Google Scholar
  12. 12.
    Lunsford LD: Letter to the editor. Glycerol rhizotomy for trigeminal neuralgia. J Neurosurg 66:151, 1987.PubMedGoogle Scholar
  13. 13.
    Arias MJ: Percutaneous retrogasserian glycerol rhizotomy for trigeminal neuralgia. A prospective study of 100 cases. J Neurosurg 65:32–36, 1986.PubMedCrossRefGoogle Scholar
  14. 14.
    Waltz TA, Copeland BR: Treatment of trigeminal neuralgia. Letter to the editor. N Engl J Med 316:693, 1987.CrossRefGoogle Scholar
  15. 15.
    Rengachary SS, Watanabe IS, Singer P, Bopp WJ: Effect of glycerol on peripheral nerve: An experimental study. Neurosurgery 6:681–688, 1983.CrossRefGoogle Scholar
  16. 16.
    Burchiel KJ, Russell LC: Glycerol neurolysis: Neurophysiological effects of topical glycerol application on rat saphenous nerve. J Neurosurg 63:784–788, 1985.PubMedCrossRefGoogle Scholar
  17. 17.
    Bennett MH, Lunsford LD: Percutaneous retrogasserian glycerol rhizotomy for tic douloureux: Part 2. Results and implications of trigeminal evoked potential studies. Neurosurgery 4:431-435, 1984.CrossRefGoogle Scholar

Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • Ronald Brisman

There are no affiliations available

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