Retrogasserian Glycerol Injection with or without Radiofrequency Electrocoagulation for Trigeminal Neuralgia

  • Ronald Brisman
Part of the Topics in Neurosurgery book series (TINS, volume 3)


Percutaneous retrogasserian injection of pure sterile glycerol into the trigeminal cistern may relieve the pain of trigeminal neuralgia without major complications [1–3]. In the initial reports, there was little numbness and major dysesthesias were rare [1, 2]. As further experience developed, it became apparent that glycerol is a denervating agent and that it could cause analgesia with bothersome dysesthesias [3–5]. Larger doses of glycerol (more than 0.25 ml) are likely to cause more denervation and dysesthesias than smaller doses.


Trigeminal Neuralgia Gasserian Ganglion Glycerol Injection Anhydrous Glycerol Initial Pain Relief 
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© Kluwer Academic Publishers 1989

Authors and Affiliations

  • Ronald Brisman

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