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Prostaglandins and Tumor Metastasis

  • Amy M. Fulton
Part of the Prostaglandins, Leukotrienes, and Cancer book series (PLAC, volume 6)

Abstract

There is considerable evidence that lipids, and specifically prostaglandins (pgs), can contribute to progressive tumor growth (1). Many studies provide evidence that lipids can contribute to early steps in carcinogenesis, in particular early promotional events. Recently, efforts have been directed towards examining the contribution prostaglandins make to the successful metastasis of tumor cells from the primary site. For breast cancer, perhaps more so than any other type of malignancy, prevention of metastasis is the ultimate clinical problem. It is also in this disease that some of the earliest evidence for a role for prostaglandins has been provided.

Keywords

Lewis Lung Carcinoma Experimental Metastasis Spontaneous Metastasis Prostaglandin Synthesis Inhibitor Amelanotic Melanoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers, Boston 1989

Authors and Affiliations

  • Amy M. Fulton
    • 1
  1. 1.E. Walter Albachten Department of ImmunologyMichigan Cancer FoundationDetroitUSA

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