Chronic Renal Failure: Definition, Causes, and Assessment

  • S. Giovannetti
  • N. Gretz
Part of the Topics in Renal Medicine book series (TIRM, volume 7)


The acronym CRF is used as a synonym for chronic renal insufficiency, chronic renal functional impairment, and also for chronic uremia, the latter term, however, having a completely different meaning (see Chapter 5). Tubular dysfunction, or abnormalities in the composition of the glomerular filtrate, are not regarded as manifestations of CRF. Thus the acronym CRF indicates a chronic reduction of glomerular filtration rate (GFR) below the normal range, corrected for a given age and body surface, irrespective of the underlying cause.


Chronic Renal Failure Lean Body Mass Creatinine Excretion Urinary Tract Obstruction Reciprocal Transformation 
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© Kluwer Academic Publishers, Boston 1989

Authors and Affiliations

  • S. Giovannetti
  • N. Gretz

There are no affiliations available

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