Limitations in Localizing and Killing Tumors Using Radiolabelled Antibodies

  • A. R. Bradwell
  • P. W. Dykes
  • A. T. M. Vaughan


Radiolabeled antibodies against tumors are being studied intensely for their use in tumor detection and tumor destruction. Although a host of different tumor types can be localized, results at present are no better than other scanning techniques. In addition no tumor has been eradicated using labelled antibodies. Dramatic improvements will depend upon a fuller understanding of tumor cell biology and optimizing all the parameters involved.


Uptake Ratio Medullary Thyroid Cancer Label Antibody Drug Antibody Conjugate Body Dose 
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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • A. R. Bradwell
    • 1
  • P. W. Dykes
    • 1
  • A. T. M. Vaughan
    • 1
  1. 1.Immunodiagnostic Research Laboratory, Department of ImmunologyThe Medical School, University of BirminghamUK

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