Monoclonal Antibodies to Gram-Negative Bacteria

  • Colin M. M. Stern

Abstract

The need to identify and classify micro-organisms, either out of scientific curiosity, clinical need or industrial necessity, has been a major pre-occupation of bacteriologists and clinicians. Many methods have been used successfully for these purposes, although the utilization of the exquisite specificity of the immune response has often given valuable results. The immune response has evolved adaptively in the face of environmental pressure exerted, in part, by micro-organisms and one arm of this response rests upon the production of antibody. However, the polyclonality of the immunoglobulins generated during an immune reaction rendered the production of specific immune reagents a tedious process of cross-absorption.

Keywords

Carbohydrate Recombination Tuberculosis Pseudomonas Meningitis 

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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Colin M. M. Stern
    • 1
  1. 1.St. Thomas’s HospitalLondonUK

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