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Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion pp 226–234Cite as

Calcium, Calcium Antagonists, Stunning, and Hibernation: An Overview

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Summary

The basic pathophysiology of stunning and hibernation differs according to the proposed role of calcium. In stunning, it is suggested that calcium overload plays a crucial role and therefore calcium antagonists may have a beneficial effect. By contrast, in hibernation, where there is an ongoing reduction in the contractile function of the myocardium, calcium antagonists may further depress the inotropic state. Ongoing research may reveal further interesting differences between stunning and hibernation.

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Authors
  1. Winifred G. Nayler
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Editors and Affiliations

  1. University of Cape Town, Cape Town, South Africa

    Lionel H. Opie MD, DPhil. (Professor of Medicine, Visiting Professor) (Professor of Medicine, Visiting Professor)

  2. Division of Cardiology, Stanford University Medical Center, Stanford, California, USA

    Lionel H. Opie MD, DPhil. (Professor of Medicine, Visiting Professor) (Professor of Medicine, Visiting Professor)

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© 1992 Kluwer Academic Publishers

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Nayler, W.G. (1992). Calcium, Calcium Antagonists, Stunning, and Hibernation: An Overview. In: Opie, L.H. (eds) Stunning, Hibernation, and Calcium in Myocardial Ischemia and Reperfusion. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1517-9_18

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  • DOI: https://doi.org/10.1007/978-1-4613-1517-9_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-7923-1793-7

  • Online ISBN: 978-1-4613-1517-9

  • eBook Packages: Springer Book Archive

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