Brain Metastases

  • Jeffrey C. Allen
Part of the Foundations of Neurological Surgery book series (FONS, volume 3)


Central nervous system (CNS) metastases from systemic cancer are usually separated into two distinct anatomic categories depending on whether they arise in the extradural or intradural spaces. The biology of metastasis differs for each of these locations, and each cancer has its own pattern of spread. Extradural or epidural metastases usually arise from a metastasis involving bone adjacent to a neural structure or from venous plexuses or lymph channels in the extradural space (figure 20-1). Intradural metastases may involve the leptomeninges, brain, or spinal cord, and are usually of hematogenous origin. This chapter reviews only the subject of parenchymal brain metastases from systemic solid tumors arising in childhood.


Osteogenic Sarcoma Brain Metastasis Pulmonary Metastasis Central Nervous System Disease Systemic Cancer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Kluwer Academic Publishers 1990

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  • Jeffrey C. Allen

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