Glucocorticoid effects on the ultrastructure of epiphyseal cartilage

  • Lyle C. Dearden
Chapter
Part of the Electron Microscopy in Biology and Medicine book series (EMBM, volume 7)

Abstract

Epiphyseal cartilage, an avascular tissue consisting of chondrocytes surrounded by an extracellular matrix, is formed in the developing embryo when mesenchymal cells group together, change their configuration, and become centers of chondrification known as precartilage. As cells enlarge and differentiate, they secrete a matrix that is metachromatic. The matrix gradually increases in amount and separates the chondroblastic cells one from another, and they then take on cytological characteristics typical of chondrocytes.

Keywords

Estrogen Osteoporosis Cortisol Dexamethasone Prostaglandin 

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Copyright information

© Kluwer Academic Publishers 1990

Authors and Affiliations

  • Lyle C. Dearden
    • 1
  1. 1.Department of Anatomy and Neurobiology College of MedicineUniversity of CaliforniaIrvineUSA

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