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Ultrastructural immunohistochemistry of noncollagenous proteins in calcified tissues

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Book cover Ultrastructure of Skeletal Tissues

Part of the book series: Electron Microscopy in Biology and Medicine ((EMBM,volume 7))

Abstract

Interest in the origin, chemistry, and properties of noncollagenous proteins in calcified tissues stands at the intersection of the two major questions related to the biology of these tissues: a) Which constitutive property makes them able to calcify in a highly controlled, orderly way? b) What makes them genetically unique in this respect among vertebrate tissues? The recent explosion of research efforts and information buildup in this area and the type of answers being sought exemplify how the overall improvement in our scientific understanding of biological facts may alter the very way in which we look at data of experience.

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Authors and Affiliations

  1. Dipartimento di Biopatologia Umana Sez Anatomia Patologica, Università “La Sapienza”, Viale Regina Elena 324 (Policlinico), I-00161, Roma, Italy

    Dr. Paolo Bianco

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  1. Dr. Paolo Bianco
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Editors and Affiliations

  1. Department of Human Biopathology, Faculty of Medicine, University “La Sapienza” of Rome, Italy

    E. Bonucci M.D.

  2. Department of Anatomy, Faculty of Medicine, University “La Sapienza” of Rome, Italy

    P. M. Motta M.D., Ph.D.

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© 1990 Kluwer Academic Publishers

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Bianco, P. (1990). Ultrastructural immunohistochemistry of noncollagenous proteins in calcified tissues. In: Bonucci, E., Motta, P.M. (eds) Ultrastructure of Skeletal Tissues. Electron Microscopy in Biology and Medicine, vol 7. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1487-5_4

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  • DOI: https://doi.org/10.1007/978-1-4613-1487-5_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8800-8

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