The insulin receptor

  • J. Espinal
Part of the Ellis Horwood Series in Biochemistry and Biotechnology book series (EMISS)


Many hormones and other extracellular stimuli exert their effects by binding to specific receptors on the plasma membrane of cells. The receptors recognize and bind the agonists with high affinity, and are therefore responsible for initiating the cascade of reactions leading to intracellular events. The hormone-receptor complex transmits this signal in various ways which are the subject of the next chapter, but which include interaction with a guanine-nucleotide-binding protein, activation of an effector enzyme, and generation of second messengers.


Tyrosine Kinase Insulin Receptor Tyrosine Residue Insulin Action Tyrosine Kinase Activity 
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© J. Espinal/Ellis Horwood Limited 1989

Authors and Affiliations

  • J. Espinal
    • 1
  1. 1.Department of EndocrinologyGlaxo Research LaboratoriesUSA

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