Advertisement

Distribution of Body Water in Rats

  • S. Yasumura
  • D. Glaros
  • J. Kalef-Ezra
  • J. Xatzikonstantinou
  • A. F. LoMonte
  • J. K. Yeh
  • R. I. Moore
Part of the Basic Life Sciences book series (BLSC, volume 55)

Abstract

Textbook values for the size of the extracellular water compartment (ECW) expressed as a fraction of total body water (TBW): ECW/TBW, range from .27 to .45 (Berne and Levy. 1988). These discrepancies are disturbing since the size of the ECW and intracellular (ICW) is inportant to the decision-making process in the management of patients with altered fluid balance, and also important in considering the pharmacokinetics of the distribution of drugs in the body.

Keywords

Neutron Activation Analysis Total Body Water Intracellular Water Tritiated Water Normal Human Subject 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Edelman, I. S., and Leibman, J., 1959, Anatomy of body water and electrolytes, Am. J. Med., 27:256.PubMedCrossRefGoogle Scholar
  2. Moore, F. D., Olesen, K. H., McKurray, J. D., Parker, H. V., Ball, M. R., and Boyden, C. M., 1963, “The Body Cell Mass and its Supporting Environment,” Saunders, Philadelphia, PA.Google Scholar
  3. Berne, R.M., and Levy, M., eds., 1987, “Physiology”, Mosby, St. LouisGoogle Scholar
  4. Valentin, N., and Olesen, K. H., 1973, Measurement of muscle tissue water and electrolytes, Scan. Clin. Lab. Invest., 32:155.CrossRefGoogle Scholar
  5. Wang, J., and Pierson, R. N., Jr., 1976, Disparate hydration and adipose and lean tissue require a new model for body water distribution in man, J. Nutr., 106:1687.PubMedGoogle Scholar
  6. Yasumura, S., Kiebzak, G. M., Ellis, K. J., LoMonte, A. F., Zhang, R., Yuen, K., and Cohn, S. H., 1987, Body composition studies in aging rats, in: “In Vivo Body Composition Studies,” K. J. Ellis, S. Yasumura, U. D. Morgan, Eds., Institute of Physical Sciences in Medicine, York, England.Google Scholar
  7. Yasumura, S., Cohn, S. H., and Ellis, K. J., 1983, Measurement of extracellular space by total body neutron activation, Am. J. Physiol., 264:R36.Google Scholar

Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • S. Yasumura
    • 1
    • 3
  • D. Glaros
    • 4
  • J. Kalef-Ezra
    • 4
  • J. Xatzikonstantinou
    • 4
  • A. F. LoMonte
    • 3
  • J. K. Yeh
    • 2
  • R. I. Moore
    • 3
  1. 1.SUNY-Health Sciences CenterBrooklynUSA
  2. 2.Winthrop University HospitalMineolaUSA
  3. 3.Brookhaven National LaboratoryUptonUSA
  4. 4.University of IoanninaIoanninaGreece

Personalised recommendations