Distribution of Body Water in Rats
Textbook values for the size of the extracellular water compartment (ECW) expressed as a fraction of total body water (TBW): ECW/TBW, range from .27 to .45 (Berne and Levy. 1988). These discrepancies are disturbing since the size of the ECW and intracellular (ICW) is inportant to the decision-making process in the management of patients with altered fluid balance, and also important in considering the pharmacokinetics of the distribution of drugs in the body.
KeywordsNeutron Activation Analysis Total Body Water Intracellular Water Tritiated Water Normal Human Subject
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