Abstract
Acute renal failure due to lead exposure was a common problem in 19th century industrial society, but is now rarely seen. The role of lead in the development or chronic renal failure is, however, less certain. Although epidemiological studies of populations exposed to lead have suggested an increased incidence of renal insufficiency in these groups, only about 1% of all cases of end-stage renal disease requiring renal replacement therapy are reported to be caused by toxic nephropathy. This may merely be due to underdiagnosis. For example, in a recent study from Belgium (Van de Vyver et al., 1988), 5% of the dialysis population were found to have bone lead concentrations that approximated levels found in active lead workers.
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References
Chettle, D.R., Scott, M.C., and Somervaille, L.J., 1989, Improvements in the precision of bone lead measurements, Phys. Med. Biol., in press.
Koster, J., Erhardt, A., Stoeppler, M., Mohl, C., and Ritz, E., 1989, Mobilizable lead in patients with chronic renal failure, Eur. J. Clin. Invest., 19:228.
Morgan, W.D., Ryde, S.J.S., Jones, S.J., Wyatt, R.M., Hainsworth, I.R., Cobbold, S., Evans, C.J., and Braithwaite, R.A., 1989, In-vivo measurements of cadmium and lead in occupationally- exposed workers and in an urban population, J. Biol. Trace Elem. Res., in press.
Somervaille, L.J., Chettle, D.R., and Scott, M.C., 1985, In vivo measurement of lead in bone using x-ray fluorescence, Phys. Med. Biol., 30:929.
Van de Vyver, F.L., D’Haese, P.C., Visser, W.J., Elseviers, M.K., Knippenberg, L.J., Lamberts, L.V., Wedeen, R.P., and DeBroe, M.E., 1988, Bone lead in dialysis patients. Kidney Int., 33:601.
Wedeen, R.P., Van de Vyver, F.L., D’Haese, P.C., Visser, W.J., Elseviers, X.M., Knippenberg, L.J., Lamberts, L.V., DeBroe, M.E., Batuman, V., Schidlovsky, G., and Jones, K., 1988, Bone lead and the diagnosis of lead nephropathy, Contr. Nephrol., 64:102.
Wittmers, L.E., Wallgren, J., Alich, A., Aufderheide, A.C., and Rapp, G., 1988, Lead in bone. IV. Distribution of lead in the human skeleton, Arch. Environ. Health., 43:381.
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© 1990 Plenum Press, New York
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Jones, S.J., Williams, A.J., Kudlac, H., Hainsworth, I.R., Morgan, W.D. (1990). The Measurement of Bone Lead Content in Patients With End Stage Renal Failure. In: Yasumura, S., Harrison, J.E., McNeill, K.G., Woodhead, A.D., Dilmanian, F.A. (eds) In Vivo Body Composition Studies. Basic Life Sciences, vol 55. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1473-8_34
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DOI: https://doi.org/10.1007/978-1-4613-1473-8_34
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