The Measurement of Bone Lead Content in Patients With End Stage Renal Failure
Acute renal failure due to lead exposure was a common problem in 19th century industrial society, but is now rarely seen. The role of lead in the development or chronic renal failure is, however, less certain. Although epidemiological studies of populations exposed to lead have suggested an increased incidence of renal insufficiency in these groups, only about 1% of all cases of end-stage renal disease requiring renal replacement therapy are reported to be caused by toxic nephropathy. This may merely be due to underdiagnosis. For example, in a recent study from Belgium (Van de Vyver et al., 1988), 5% of the dialysis population were found to have bone lead concentrations that approximated levels found in active lead workers.
KeywordsRenal Replacement Therapy Lead Exposure Bone Biopsy Flame Atomic Absorption Spectrometry Lead Measurement
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