Clinical Studies of Total Body Nitrogen in an Australian Hospital
The first reports of the measurement of Total Body Nitrogen (TBN) by In Vivo Neutron Activation Analysis (IVNAA) using a cyclotron date from the early 1970’s (Harvey et al., 1973). By the late 1970’s other laboratories were using the prompt gamma IVNAA technique with isotopic neutron sources (Mernagh et al., 1977; Vartsky et al., 1979a). The prompt IVNAA method is a relatively simple, non-invasive test which requires approximately 20 minutes of the patient’s time. The radiation dose is minimal, and both capital and running costs are small. Clinically, Total Body Protein (TBPr) can be reliably estimated from TBN (TBPr = 6.25 × TBN). The many clinical applications of the technique are described by Wahlqvist and Marks elsewhere in this volume, and by McNeill (1988). It is therefore surprising that so few hospitals are currently using the technique.
KeywordsShort Bowel Syndrome Chronic Obstructive Lung Disease Home Parenteral Nutrition Short Bowel Syndrome Patient Monash Medical
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- Allen, B. J., Bailey, G.M., and McGregor, B.J., 1985. Dose equivalent distributions in the AAEC total body nitrogen facility, Fourth Australian Conference on Science and Engineering. Lucas Heights, 6-8 Nov 1985.Google Scholar
- McNeill, K.G., 1988. Current techniques and applications of body composition analysis at Toronto General Hospital, Australasian Physical and Engineering Sciences in Medicine, 11: 15.Google Scholar
- Vartsky, D., Ellis, K. J., Cohn. S. H., 1979a. In vivo measurement of body nitrogen by analysis of prompt gammas from neutron capture, J. Nucl. Med. 20: 1158.Google Scholar