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Reverse Transcriptase: Mediator of Genomic Plasticity

  • Chapter
Molecular Evolution of Viruses — Past and Present

Abstract

Reverse transcription has been an important mediator of genomic change. This influence dates back more than three billion years, when the RNA genome was converted into the DNA genome. While the current cellular role(s) of reverse transcriptase are not yet completely understood, it has become clear over the last few years that this enzyme is still responsible for generating significant genomic change and that its activities are one of the driving forces of evolution. Reverse transcriptase generates, for example, extra gene copies (retrogenes), using as a template mature messenger RNAs. Such retrogenes do not always end up as nonfunctional pseudogenes but form, after reinsertion into the genome, new unions with resident promoter elements that may alter the gene’s temporal and/or spatial expression levels. More frequently, reverse transcriptase produces copies of nonmessenger RNAs, such as small nuclear or cytoplasmic RNAs. Extremely high copy numbers can be generated by this process. The resulting reinserted DNA copies are therefore referred to as short interspersed repetitive elements (SINEs). SINEs have long been considered selfish DNA, littering the genome via exponential propagation but not contributing to the host’s fitness. Many SINEs, however, can give rise to novel genes encoding small RNAs, and are the migrant carriers of numerous control elements and sequence motifs that can equip resident genes with novel regulatory elements [Brosius J. and Gould S.J., Proc Natl Acad Sci USA 89, 10706–10710, 1992]. Retrosequences, such as SINEs and portions of retroelements (e.g., long terminal repeats, LTRs), are capable of donating sequence motifs for nucleosome positioning, DNA methylation, transcriptional enhancers and silencers, poly(A) addition sequences, determinants of RNA stability or transport, splice sites, and even amino acid codons for incorporation into open reading frames as novel protein domains. Retroposition can therefore be considered as a major pacemaker for evolution (including speciation). Retroposons, with their unique properties and actions, form the molecular basis of important evolutionary concepts, such as exaptation [Gould S.J. and Vrba E., Paleobiology 8, 4–15, 1982] and punctuated equilibrium [Elredge N. and Gould S.J. in Schöpf T.J.M. (ed). Models in Paleobiology. Freeman, Cooper, San Francisco, 1972, pp. 82–115].

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References

  1. Temin H.M. and Mitztani S., Nature 226, 1211–1213, 1970.

    PubMed  CAS  Google Scholar 

  2. Baltimore D., Nature 226, 1209–1211, 1970.

    PubMed  CAS  Google Scholar 

  3. Doolittle R.F. and Feng D.F., Curr Top Microbiol Immunol 176, 195–211, 1992.

    PubMed  CAS  Google Scholar 

  4. Temin H.M., Cell 27, 599–600, 1980.

    Google Scholar 

  5. Flavell A.J., Comp Biochem Physiol Biochem Mol Biol 110, 3–15, 1995.

    CAS  Google Scholar 

  6. Woese C.R., The Origins of the Genetic Code. Harper & Row, New York, 1967.

    Google Scholar 

  7. Crick F., J Mol Biol 38, 367–379, 1968.

    PubMed  CAS  Google Scholar 

  8. Orgel L., J Mol Biol 38, 381–393, 1968.

    PubMed  CAS  Google Scholar 

  9. Gilbert W., Nature 319, 618, 1986.

    Google Scholar 

  10. Eigen M. and Schuster P., J Mol Evol 19, 47–61, 1982.

    PubMed  CAS  Google Scholar 

  11. Darnell J.E. and Doolittle W.F., Proc Natl Acad USA 83, 1271–1275, 1986.

    CAS  Google Scholar 

  12. Maizels N. and Weiner A.M., Proc Natl Acad Sci USA 91, 6729–6734, 1994.

    PubMed  CAS  Google Scholar 

  13. Blackburn, E.H., Annu Rev Biochem 61, 113–129, 1992.

    PubMed  CAS  Google Scholar 

  14. Dombroski B.A., Mathias S.L., Nanthakumar E., Scott A.F., and Kazazian H.H. Jr., Science 254, 1805–1808, 1991.

    PubMed  CAS  Google Scholar 

  15. Mathias S.L., Scott A.F., Kazazian H.H. Jr., Boeke J.D., and Gabriel A., Science 254, 1808–1810, 1991.

    PubMed  CAS  Google Scholar 

  16. Inouye S., Hsu M.-Y., Eagle S., and Inouye M., Cell 56, 709–717, 1989.

    PubMed  CAS  Google Scholar 

  17. Lampson B.C., Sun J., Hsu M.-Y., Vallejo-Ramirez J., Inouye S., and Inouye M., Science 243, 1033–1038, 1989.

    PubMed  CAS  Google Scholar 

  18. Lim D. and Maas W.K., Cell 56, 891–904, 1989.

    PubMed  CAS  Google Scholar 

  19. Temin H.M., Nature 339, 254–255, 1989.

    PubMed  CAS  Google Scholar 

  20. Temin H.M., Perspect Biol Med 14, 11–26, 1970.

    PubMed  CAS  Google Scholar 

  21. Jacob F., Science 196, 1161–1166, 1977.

    PubMed  CAS  Google Scholar 

  22. Jacob F., in Evolution from Molecules to Men. Bendall D.S. (ed). Cambridge University Press, Cambridge, 1983, pp. 131–144.

    Google Scholar 

  23. Scarpulla R.C., Mol Cell Biol 4, 2279–2288, 1984.

    PubMed  CAS  Google Scholar 

  24. Georgiev G.P., Eur J Biochem 145, 203–220, 1984.

    PubMed  CAS  Google Scholar 

  25. Baltimore D., Cell 40, 481–482, 1985.

    PubMed  CAS  Google Scholar 

  26. McDonald J.F., BioScience 40, 183–191, 1990.

    Google Scholar 

  27. McDonald J.F., Curr Opin Genet Dev 3, 855–864, 1993.

    PubMed  CAS  Google Scholar 

  28. Steele E.J. and Pollard J.W., Mol Immunol 24, 667–673, 1987.

    PubMed  CAS  Google Scholar 

  29. Steele E.J., Somatic Selection and Adaptive Evolution. On the Inheritance of Acquired Characters. University of Chicago Press, Chicago, 1979.

    Google Scholar 

  30. Cairns J., Overbaugh J., and Miller S., Nature 289, 353–357, 1988.

    Google Scholar 

  31. Koch A.L., Genetics 72, 297–316, 1988.

    Google Scholar 

  32. Rigby P.J.J., Burleigh B.D. Jr., and Hartley B.S., Nature 257, 200–204, 1974.

    Google Scholar 

  33. McClintock B., The Discovery and Characterization of Transposable Elements: The Collected Papers of Barbara McClintock. Garland, New York, 1987.

    Google Scholar 

  34. Gould S.J. and Vrba E., Paleobiology 8, 4–15, 1982.

    Google Scholar 

  35. Linial M., Cell 49, 93–102, 1987.

    PubMed  CAS  Google Scholar 

  36. Dornburg R. and Temin H.M., Mol Cell Biol 8, 2328–2334, 1988.

    PubMed  CAS  Google Scholar 

  37. Carlton M.B., Colledge W.H., and Evans M.J., Mamm Genome 6, 90–95, 1995.

    PubMed  CAS  Google Scholar 

  38. Tchénio T., Segal-Bendirdjian E., and Heidmann T., EMBO J 12, 1487–1497, 1993.

    PubMed  Google Scholar 

  39. Labuda D., Zietkiewicz E., and Mitchell G.A., in Maraia R. (ed). The Impact of Short Interspersed Elements (SINEs) on the Host Genome. R.G. Landes, Austin, TX, 1995, pp. 1–24.

    Google Scholar 

  40. Lehrman M.A., Schneider W.J., Südhof T.C., Brown M.S., Goldstein J.L., and Russell D.W., Science 227, 140–146, 1985.

    PubMed  CAS  Google Scholar 

  41. Muratani K., Hada T., Yamamoto Y., Kaneko T., Shigeto Y., Ohue T., Furuyama J., and Higashino K., Proc Natl Acad Sci USA 88, 11315–11319, 1991.

    PubMed  CAS  Google Scholar 

  42. Amariglio N. and Rechavi G., Envir Mol Mutagen 27, 212–218, 1993.

    Google Scholar 

  43. Wilke CM., Maimer E., and Adams J., Genetica 86, 155–173, 1992.

    PubMed  CAS  Google Scholar 

  44. Woodruff R.C., Genetica 86, 143–154, 1992.

    PubMed  CAS  Google Scholar 

  45. Kim A., Terzian C, Santamaría P., Pelisson A., Prud’homme N., and Bucheton A., Proc Natl Acad Sci USA 97, 1285–1289, 1994.

    Google Scholar 

  46. Weiner A.M., Deininger P.L., and Efstratiadis A., Annu Rev Biochem 55, 631–661, 1986.

    PubMed  CAS  Google Scholar 

  47. Britten R.J. and Davidson E.H., Science 165, 349–357, 1969.

    PubMed  CAS  Google Scholar 

  48. Britten R.J. and Davidson E.H., Q Rev Biol 46, 111–133, 1971.

    PubMed  CAS  Google Scholar 

  49. Singer M.F., Cell 28, 433–434, 1982.

    PubMed  CAS  Google Scholar 

  50. Doolittle W.F. and Sapienza C, Nature 284, 601–603, 1980.

    PubMed  CAS  Google Scholar 

  51. Orgel L.E. and Crick F.H.C., Nature 284, 604–607, 1980.

    PubMed  CAS  Google Scholar 

  52. Deininger P., in Howe M. and Berg D. (eds). Mobile DNA. ASM Publications, 1989, pp. 619–636.

    Google Scholar 

  53. Deininger P.L., Batzer M.A., Hutchison C.A. III, and Edgell M.H., Trends Genet 8, 307–311, 1992.

    PubMed  CAS  Google Scholar 

  54. Deininger P., Tiedge H., Kim J., and Brosius J., Prog Nucleic Acids Res Mol Biol 52, 67–88, 1996.

    CAS  Google Scholar 

  55. Schmid C.W. and Maraia R., Curr Opin Genet Dev 2, 874–882, 1992.

    PubMed  CAS  Google Scholar 

  56. Deininger P.L. and Batzer M.A., in Maraia R. (ed). The Impact of Short Interspersed Elements (SINEs) on the Host Genome. R.G. Landes, Austin, TX, 1995, pp. 43–60.

    Google Scholar 

  57. Kim J., Martignetti J.A., Shen M.R., Brosius J., and Deininger P.L., Proc Natl Acad Sci USA 91, 3607–3611, 1994.

    PubMed  CAS  Google Scholar 

  58. Kim J., Kass D.H., and Deininger P.L., Nucleic Acids Res 23, 2245–2251, 1995.

    PubMed  CAS  Google Scholar 

  59. Rogers J., Int Rev Cytol 93, 187–279, 1985.

    PubMed  CAS  Google Scholar 

  60. Piechaczyk M., Blanchard J.M., Riaad-El Sabouty S., Dani C, Marty L., and Jeanteur P., Nature 312, 469–471, 1984.

    PubMed  CAS  Google Scholar 

  61. Ullu E. and Weiner A.M., EMBO J 3, 3303–3310, 1984.

    PubMed  CAS  Google Scholar 

  62. Okada N., Curr Opin Genet Dev 1, 498–504, 1993.

    Google Scholar 

  63. Ohshima K. and Okada N., J Mol Biol 243, 25–27, 1994.

    PubMed  CAS  Google Scholar 

  64. Okada N. and Ohshima K., in Maraia R. (ed). The Impact of Short Interspersed Elements (SINEs) on the Host Genome. R.G. Landes, Austin, TX, 1995, pp. 61–79.

    Google Scholar 

  65. Charlesworth B., Sniegowski P., and Stephan W., Nature 371, 215–220, 1994.

    PubMed  CAS  Google Scholar 

  66. Howard B.H. and Sakamoto B.H., New Biol 2, 759–770, 1990.

    PubMed  CAS  Google Scholar 

  67. Brosius J., Science 252, 753, 1991.

    Google Scholar 

  68. Brosius J. and Gould S.J., Proc Natl Acad Sci USA 89, 10706–10710, 1992.

    PubMed  CAS  Google Scholar 

  69. Zuckerkandl E., J Mol Evol 34, 259–271, 1992.

    PubMed  CAS  Google Scholar 

  70. Banville D., Rotaru M., and Boie Y., Genetica 86, 85–97, 1992.

    PubMed  CAS  Google Scholar 

  71. Shapiro J.A., Genetica 86, 99–111, 1992.

    PubMed  CAS  Google Scholar 

  72. King C.C., Genetica 86, 99–111, 1992.

    Google Scholar 

  73. Robins D.M. and Samuelson L.C., Genetica 86, 191–201, 1992.

    PubMed  CAS  Google Scholar 

  74. von Sternberg R.M., Novick G.E., Gao G.-P., and Herrera R.J., Genetica 86, 215–246, 1992.

    Google Scholar 

  75. Hickey D.A., Genetica 86, 269–274, 1992.

    PubMed  CAS  Google Scholar 

  76. Wichman H.A., van den Busche R.A., Hamilton M.J., and Baker R.J., Genetica 86, 287–293, 1992.

    PubMed  CAS  Google Scholar 

  77. Nouvel P., Genetica 93, 191–201, 1994.

    PubMed  CAS  Google Scholar 

  78. Novak R., Science 263, 608–610, 1994.

    Google Scholar 

  79. Maraia R.J. (ed)., The Impact of Short Interspersed Elements (SINEs) on the Host Genome. R.G. Landes, Austin, TX, 1995.

    Google Scholar 

  80. Brosius J. and Gould S.J., Nature 365, 102, 1993.

    PubMed  CAS  Google Scholar 

  81. Lewis E.B., Cold Spring Harbor Symp Quant Biol 16, 159–174, 1951.

    PubMed  CAS  Google Scholar 

  82. Ohno S., Evolution by Gene Duplication. Springer, New York, 1970.

    Google Scholar 

  83. Zuckerkandl E., Biochimie 54, 1095–1102, 1972.

    PubMed  CAS  Google Scholar 

  84. Gilbert W., Nature 271, 501, 1978.

    PubMed  CAS  Google Scholar 

  85. Parma J., Christophe D., Pohl V., and Vassart G., J Mol Biol 196, 769–779, 1987.

    PubMed  CAS  Google Scholar 

  86. Keese P.K. and Gibbs A., Proc Natl Acad Sci USA 89, 9849–9493, 1992.

    Google Scholar 

  87. White S.H. and Jacobs R.E., J Mol Evol 36, 79–95, 1993.

    PubMed  CAS  Google Scholar 

  88. White S.H., J Mol Evol 38, 383–394, 1994.

    PubMed  CAS  Google Scholar 

  89. Makalowski W., Mitchell G.A., and Labuda D., Trends Genet 10, 188–193, 1994.

    PubMed  CAS  Google Scholar 

  90. Makalowski W., in Maraia R. (ed). The Impact of Short Interspersed Elements (SINEs) on the Host Genome. R.G. Landes, Austin, TX, 1995, pp. 81–104.

    Google Scholar 

  91. Ashworth A., Skene B., Swift S., and Lovell-Badge R., EMBO J 9, 1529–1534, 1990.

    PubMed  CAS  Google Scholar 

  92. Persson K., Holm I., and Heby O., J Biol Chem 270, 5642–5648, 1995.

    PubMed  CAS  Google Scholar 

  93. Fourel G., Trepo C, Bougueleret L., Henglein B., Ponzetto A., Tiollais P., and Buendia M.A., Nature 347, 294–298, 1990.

    PubMed  CAS  Google Scholar 

  94. Soares M.B., Schon E., Henderson A., Karathanasis S.K., Cate R., Zeitlin S., Chirgwin J., and Efstratiadis A., Mol Cell Biol 5, 2090–2103, 1985.

    PubMed  CAS  Google Scholar 

  95. Clark B.D., Collins K.L., Gandy M.S., Webb A.C., and Auron P.E., Nucleic Acids Res. 14, 7897–7914, 1986.

    CAS  Google Scholar 

  96. O’Brien S.J., Genetic Maps. Book 5, Human Maps. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1990.

    Google Scholar 

  97. Wilkie T.M., Gilbert D.J., Olsen A.S., Chen X.-N., Armatruda T.T., Korenberg J.R., Trask B.J., de Jong P., Reed R.R., Simon M.I., Jenkins N.A., and Copeland N.G., Nature Genet 1, 85–91, 1992.

    PubMed  CAS  Google Scholar 

  98. Dyer M.R., Gay N.J., and Walker J.E., Biochem J 260, 249–258, 1989.

    PubMed  CAS  Google Scholar 

  99. McCarrey J.R. and Thomas K., Nature 526, 501–505, 1987.

    Google Scholar 

  100. Boer P.H., Adra C.N., Lau Y.-F., and McBurney M.W., Mol Cell Biol 7, 3107–3112, 1987.

    PubMed  CAS  Google Scholar 

  101. Adra C.N., Ellis N.A., and McBurney M.W., Somat Cell Mol Genet 14, 69–81, 1988.

    PubMed  CAS  Google Scholar 

  102. McCarrey J.R., Nucleic Acids Res 18, 949–944, 1990.

    PubMed  CAS  Google Scholar 

  103. Carlson D.P. and Ross J., Proc Natl Acad Sci USA 81, 7782–7786, 1984.

    PubMed  CAS  Google Scholar 

  104. Allan M. and Paul J., Nucleic Acids Res 12, 1193–1200, 1984.

    PubMed  CAS  Google Scholar 

  105. Arai Y., Mukai T., and Hori K., Biochim Biophys Acta 1007, 91–98, 1989.

    PubMed  CAS  Google Scholar 

  106. Luoh S.-W. and Page D., Genomics 19, 310–319, 1994.

    PubMed  CAS  Google Scholar 

  107. Dahl H.-H.M., Brown R.M., Hutchison W.M., Maragos C, and Brown G.K., Genomics 8, 225–232, 1990.

    PubMed  CAS  Google Scholar 

  108. Brown R.M., Dahl H.-H.M., and Brown G.K., Somat Cell Mol Genet 16, 487–492, 1990.

    PubMed  CAS  Google Scholar 

  109. Fitzgerald J., Hutchison W.M., and Dahl H.-H.M., Biochim Biophys Acta 1131, 83–90, 1992.

    PubMed  CAS  Google Scholar 

  110. Fitzgerald J., Wilcox S.A., Marshall-Graves J.A., and Dahl H.-H.M., Genomics 18, 636–642, 1993.

    PubMed  CAS  Google Scholar 

  111. Shashidharan P., Michaelidis T.M., Robakis N.K., Kresovali A., Papamatheakis J., and Plaitakis A., J Biol Chem 269, 16971–16976, 1994.

    PubMed  CAS  Google Scholar 

  112. Monesi V., J Reprod Fertil 13, 1–14, 1971.

    Google Scholar 

  113. Sugiyama A., Kume A., Nemoto K., Lee S.Y., Asami Y., Nemoto F., Nishimura S., and Kuchino Y., Proc Natl Acad Sci USA 86, 9144–9148, 1989.

    Google Scholar 

  114. Morton C.C., Nussenzweig M.C., Sousa R., Sorenson G.D., Pettengill O.S., and Shows T.B., Genomics 4, 367–375, 1989.

    PubMed  CAS  Google Scholar 

  115. Sugiyama A., Miyagi Y., Shirasawa Y., and Kuchino Y., Oncogene 6, 2027–2032, 1989.

    Google Scholar 

  116. Zimmerman K.A., Yancopoulos G.D., Collum R.G., Smith R.K., Kohl N.E., Denis K.A., Nau M.M., Witte O.N., Toran-Allerand D., Gee C.E., Minna J.D., and Alt F.W., Nature 319, 780–783, 1986.

    PubMed  CAS  Google Scholar 

  117. Fourel G., Transy C., Tennant B.C., and Buendia M.A., Mol Cell Biol 12, 5336–5344, 1992.

    PubMed  CAS  Google Scholar 

  118. Sturm R.A. and Herr W., Nature 336, 601–604, 1988.

    PubMed  CAS  Google Scholar 

  119. Sturm R.A., Cassady J.L., Das G., Romo A., and Evans G.A., Genomics 16, 333–3341, 1993.

    PubMed  CAS  Google Scholar 

  120. Kuhn R., Monuki E.S., and Lemke G., Mol Cell Biol 11, 4642–4650, 1991.

    PubMed  CAS  Google Scholar 

  121. Hara Y., Rovescalli A.C., Kim Y., and Nirenberg M., Proc Natl Acad Sci USA 89, 3280–3284, 1992.

    PubMed  CAS  Google Scholar 

  122. Theil T., Zechner U., Klett C, Adolph S., and Moroy T., Cytogenet Cell Genet 66, 267–271, 1994.

    PubMed  CAS  Google Scholar 

  123. Nojima H., J Mol Biol 208, 269–282, 1989.

    PubMed  CAS  Google Scholar 

  124. Fischer R., Koller M., Flura M., Mathews S., Strehler-Page M.-A., Krebs J., Penniston J.T., Carafoli E., and Strehler E.E., J Biol Chem 263, 17055–17062, 1988.

    PubMed  CAS  Google Scholar 

  125. Stein J.P., Munjaal R.P., Lagace L., Lai E.C., O’Malley B.W., and Means A.R., Proc Natl Acad Sci USA 80, 6485–6489, 1983.

    PubMed  CAS  Google Scholar 

  126. Putkey J.A., Carroll S.L., and Means A.R., Mol Cell Biol 7, 1549–1553, 1987.

    PubMed  CAS  Google Scholar 

  127. Koller M. and Strehler E.E., FEBS Lett 239, 121–128, 1988.

    PubMed  CAS  Google Scholar 

  128. Yaswen P., Smoll A., Hosuda J., Parry G., and Stampfer M.R., Cell Growth Differ 3, 335–345, 1992.

    PubMed  CAS  Google Scholar 

  129. Lewin R., Science 279, 1052–1054, 1983.

    Google Scholar 

  130. Rhyner J.A., Koller M., Durussel-Gerber I., Cox J.A., and Strehler E.E., Biochemistry 31, 12826–12832, 1992.

    PubMed  CAS  Google Scholar 

  131. Edman C.F., George S.E., Means A.R., Schulman H., and Yaswen P., Eur J Biochem 226, 725–730, 1994.

    PubMed  CAS  Google Scholar 

  132. Harris E., Yaswen P., and Thorner J., Mol Gen Genet 247, 137–147, 1995.

    PubMed  CAS  Google Scholar 

  133. Linnenbach A.J., Seng B.A., Wu S., Robbins S., Scollon M., Pyrc J.J., Druck T., and Huebner K., Mol Cell Biol 13, 1507–1515, 1993.

    PubMed  CAS  Google Scholar 

  134. Renaudie F., Yachou A.-K., Grandchamp B., Jones R., and Beaumont C., Mamm Genome 2, 143–149, 1992.

    PubMed  CAS  Google Scholar 

  135. Devilat I. and Carvello P., FEBS Lett 316, 114–118, 1993.

    PubMed  CAS  Google Scholar 

  136. Sargent C.A., Young C., Marsh S., Ferguson-Smith M.A., and Affara N.A., Hum Mol Genet 3, 1317–1324, 1994.

    PubMed  CAS  Google Scholar 

  137. Wiese S., Murphy D.B., Schlung A., Burfeind P., Schmundt D., Schnülle V., Mattei M.-G., and Thies U., Biochim Biophys Acta 1262, 105–112, 1995.

    PubMed  Google Scholar 

  138. Wenger R.H., Kieffer N., Wicki A.N., and Clemetson K.J., Biochem Biophys Res Comm 156, 389–395, 1991.

    Google Scholar 

  139. Bhandari B., Roesler W.J., DeLisio K.D., Klemm D.J., Ross N.S., and Miller R.E., J Biol Chem 266, 7784–7792, 1991.

    PubMed  CAS  Google Scholar 

  140. Chakrabarti R., McCracken J.B., Chakrabarti D., and Souba W.W., Gene 153, 163–199, 1995.

    PubMed  CAS  Google Scholar 

  141. Bard J.A., Nawoschik S.P., O’Dowd B.F., George S.R., Branchek T.A., and Weinshank R.L., Gene 153, 295–296, 1995.

    PubMed  CAS  Google Scholar 

  142. Nugent J.M. and Palmer J.D., Cell 66, 473–481, 1991.

    PubMed  CAS  Google Scholar 

  143. Long M. and Langley C.H., Science 260, 91–95, 1993.

    PubMed  CAS  Google Scholar 

  144. Fink G.R., Cell 49, 5–6, 1988.

    Google Scholar 

  145. Derr L.K. and Strathern J.N., Nature 361, 170–173, 1993.

    PubMed  CAS  Google Scholar 

  146. Hamann K.J., Ten R.M., Loegering D.A., Jenkins R.B., Heise M.T., Schad CR., Pease L.R., Gleich G.J., and Barker R.L., Genomics 7, 535–546, 1990.

    PubMed  CAS  Google Scholar 

  147. Kedes L.H., Annu Rev Biochem 48, 837–870, 1979.

    PubMed  CAS  Google Scholar 

  148. Hentschel C.C. and Birnstiel M.L., Cell 25, 301–313, 1981.

    PubMed  CAS  Google Scholar 

  149. Nagata S., Mantei N., and Weissman C, Nature 287, 401–408, 1980.

    PubMed  CAS  Google Scholar 

  150. Lawn R.M., Adelman J., Frank A.E., Houck C.H., Gross M., Najarían R., and Goeddel D.V., Nucleic Acids Res 9, 1045–1052, 1981.

    PubMed  CAS  Google Scholar 

  151. Henco K., Brosius J., Fujisawa A., Fujisawa J.-I., Haynes J.R., Hochstadt J., Kovacic T., Pasek M., Schamböck A., Schmid J., Todokoro K., Wälchli M., Nagata S., and Weissman C, J Mol Biol 185, 227–260, 1985.

    PubMed  CAS  Google Scholar 

  152. Strong M., Chandy K.G., and Gutman G.A., Mol Biol Evol 10, 221–242, 1993.

    PubMed  CAS  Google Scholar 

  153. Dal Toso R., Sommer B., Ewert M., Herb A., Pritchett D.B., Bach A., Shivers B.D., and Seeburg P.H., EMBO J. 8, 4025–4034, 1989.

    Google Scholar 

  154. Kobilka B.K., Frielle T., Collins S., Yang-Feng T., Kobilka T.S., Francke U., Lefkowitz R.J., and Caron M.G., Nature 329, 75–79, 1987.

    PubMed  CAS  Google Scholar 

  155. Sunahara R.K., Niznik H.B., Weiner D.M., Stormann T.M., Brann M.R., Kennedy J.L., Gelernter J.E., Rozmahel R., Yang Y., Israel Y., Seeman P., and O’Dowd B.F., Nature 347, 80–83, 1990.

    PubMed  CAS  Google Scholar 

  156. Grandy D.K., Zhang Y., Bouvier C, Zhou Q.-Y., Johnson R.A., Allen L., Buck K., Bunzow J.R., Salon J., and Civelli, O., Proc Natl Acad Sci USA 88, 9175–9179, 1991.

    PubMed  CAS  Google Scholar 

  157. Buck L. and Axel R., Cell 65, 175–187, 1991.

    PubMed  CAS  Google Scholar 

  158. DeChiara T.M. and Brosius J., Proc Natl Acad Sci USA 84, 2624–2628, 1987.

    PubMed  CAS  Google Scholar 

  159. Watson J.B. and Sutcliffe J.G., Mol Cell Biol 7, 3324–3327, 1987.

    PubMed  CAS  Google Scholar 

  160. Martignetti J.A. and Brosius J., Proc Natl Acad Sci USA 90, 9698–9702, 1993.

    PubMed  CAS  Google Scholar 

  161. Martignetti J.A. and Brosius J., Proc Natl Acad Sci USA 90, 11563–11567, 1993.

    PubMed  CAS  Google Scholar 

  162. Tiedge H., Chen W., and Brosius J., J Neurosci 13, 2382–2390, 1993.

    PubMed  CAS  Google Scholar 

  163. Martignetti J.A. and Brosius J., Mol Cell Biol 15, 1642–1650, 1995.

    PubMed  CAS  Google Scholar 

  164. Tiedge H., Fremeau R.T. Jr., Weinstock P.H., Arancio O., and Brosius J., Proc Natl Acad Sci USA 88, 2093–2097, 1991.

    PubMed  CAS  Google Scholar 

  165. Tiedge H., Zhou A., Thorn N., and Brosius J., J Neurosci 13, 4214–4219, 1993.

    PubMed  CAS  Google Scholar 

  166. Russo T., Costanzo F., Oliva A., Ammendola R., Duilio A., Esposito F., and Cimino F., Eur J Biochem 158, 437–442, 1986.

    PubMed  Google Scholar 

  167. Brosius J. and Tiedge H., in Localized RNAs. Lipshitz H.D. (ed). R.G. Landes, Austin, TX, 1995, 289–300.

    Google Scholar 

  168. Steward O. and Banker G.A., Trends Neurosci 15, 180–186, 1992.

    PubMed  CAS  Google Scholar 

  169. Steward O., Proc Natl Acad Sci USA 91, 10766–10768, 1994.

    PubMed  CAS  Google Scholar 

  170. Kobayashi S., Goto S., and Anzai K., J Biol Chem 226, 4726–4730, 1991.

    Google Scholar 

  171. Cheng J.-G., Tiedge H., and Brosius J., Soc Neurosci Abstr 17, 379, 1992.

    Google Scholar 

  172. Cheng J.-G., Tiedge H., and Brosius J., DNA Cell Biol, 1996, in press.

    Google Scholar 

  173. Labuda D. and Zietkiewicz E., J Mol Evol 39, 506–518, 1994.

    PubMed  Google Scholar 

  174. Maraia R.J. and Sarrowa J., in: Maraia R. (ed). The Impact of Short Interspersed Elements (SINEs) on the Host Genome. R.G. Landes, Austin, TX, 1995, pp. 163–196.

    Google Scholar 

  175. Bovia F., Fornallaz M., Leffers H., and Strub K., Mol Cell Biol 15, 1995, in press.

    Google Scholar 

  176. Fuke M., Hendrix L.C., and Bollon A.P., Gene 32, 135–140, 1984.

    PubMed  CAS  Google Scholar 

  177. Seiser C, Beck G., and Wintersberger E., FEBS Lett 270, 123–126, 1990.

    PubMed  CAS  Google Scholar 

  178. Adrey N.B., Tollefsbol T.O., Sparks A.B., Edgell M.H., and Hutchison C.A. III, Proc Natl Acad Sci USA 91, 1569–1573, 1994.

    Google Scholar 

  179. Reynaud C.-A., Anquez V., Grimai H., and Weill J.-C, Cell 48, 379–388, 1987.

    PubMed  CAS  Google Scholar 

  180. McCormack W.T., Hurley E.A., and Thompson C.B., Mol Cell Biol 13, 821–830, 1993.

    PubMed  CAS  Google Scholar 

  181. Longacre S. and Eisen H., EMBO J 5, 1057–1063, 1986.

    PubMed  Google Scholar 

  182. Roth C, Longacre S., Raibaud A., Baltz T., and Eisen H., EMBO J 5, 1065–1070, 1986.

    PubMed  CAS  Google Scholar 

  183. Roth C, Bringaud F., Layden R.E., Baltz T., and Eisen H., Proc Natl Acad Sci USA 86, 9375–9379, 1989.

    PubMed  CAS  Google Scholar 

  184. Stenzel-Poore M.P. and Rittenberg M.B., J Immunol 138, 3055–3059, 1987.

    PubMed  CAS  Google Scholar 

  185. Marshall C.R., Raff E.C., and Raff R.A., Proc Natl Acad Sci USA 91, 12283–12287, 1994.

    PubMed  CAS  Google Scholar 

  186. Kim J.H., Yu C.-Y., Bailey A., Hardison R., and Shen C.-K.J., Nucleic Acids Res 17, 5687–5700, 1989.

    PubMed  CAS  Google Scholar 

  187. Hakim I., Amariglio N., Grossman Z., Simoni-Brok F., Ohno S., and Rechavi G., Proc Natl Acad Sci USA 91, 7967–7969, 1994.

    PubMed  CAS  Google Scholar 

  188. Liu W.M. and Schmid C, Nucleic Acids Res 21, 1351–1359, 1993.

    PubMed  CAS  Google Scholar 

  189. Kochanek S., Renz D., and Doerfler W., EMBO J 12, 1141–1151, 1993.

    PubMed  CAS  Google Scholar 

  190. Schmid C.W. and Rubin CM., in Maraia R. (ed). The Impact of Short Interspersed Elements (SINEs) on the Host Genome. R.G. Landes, Austin, TX, 1995, pp. 105–123.

    Google Scholar 

  191. Humphrey G.W., in Maraia R. (ed). The Impact of Short Interspersed Elements (SINEs) on the Host Genome. R.G. Landes, Austin, TX, 1995, pp. 195–222.

    Google Scholar 

  192. Bird P.A., Cell 70, 5–8, 1992.

    PubMed  CAS  Google Scholar 

  193. Tomilin N.V., Bozhkov V.M., Bradbury E.M., and Schmid C.W., Nucleic Acids Res 20, 2941–2945, 1992.

    PubMed  CAS  Google Scholar 

  194. Cockerill P.N., Nucleic Acids Res 18, 2643–2648, 1990.

    PubMed  CAS  Google Scholar 

  195. Englander E.W., Wolffe A.P., and Howard B.H., J Biol Chem 268, 19565–19573, 1993.

    PubMed  CAS  Google Scholar 

  196. Englander E.W. and Howard B.H., J Biol Chem 270, 10091–10096, 1995.

    PubMed  CAS  Google Scholar 

  197. Howard B.H., Russanova V.R., and Englander E.W., in Maraia R. (ed). The Impact of Short Interspersed Elements (SINEs) on the Host Genome. R.G. Landes, Austin, TX, 1995, pp. 133–141.

    Google Scholar 

  198. Valgeirdottír K., Traverse-Lahey K., and Pardue M.L., Proc Natl Acad Sci USA 87, 7998–8002, 1990.

    Google Scholar 

  199. Levis R.W., Ganesan R., Houtchens K., Tolar L.A., and Sheen F.-M., Cell 75, 1083–1093, 1993.

    PubMed  CAS  Google Scholar 

  200. Panning B. and Smiley J.R., in Maraia R. (ed). The Impact of Short Interspersed Elements (SINEs) on the Host Genome. R.G. Landes, Austin, TX, 1995, pp. 143–161.

    Google Scholar 

  201. Gilbert W., Science 228, 823–824, 1985.

    PubMed  CAS  Google Scholar 

  202. Gilbert W., Cold Spring Harbor Symp Quant Biol 52, 901–905, 1987.

    PubMed  CAS  Google Scholar 

  203. Matsuo K., Clay O., Kunzler P., Georgiev O., Urbanek P., and Schaffner W., Biol Chem Hoppe Seyler 375, 675–683, 1994.

    PubMed  CAS  Google Scholar 

  204. Brookfield J.F.Y., Curr Biol 5, 255–256, 1995.

    PubMed  CAS  Google Scholar 

  205. Emi M., Hori A., Tomita N., Nishide T., Ogawa M., Mori T., and Matsubara K., Gene 62, 229–235, 1988.

    PubMed  CAS  Google Scholar 

  206. Samuelson L., Wiebauer K., Snow CM., and Meisler M.H., Mol Cell Biol 10, 2513–2520, 1990.

    PubMed  CAS  Google Scholar 

  207. Ting C.-N., Rosenberg M.P., Snow CM., Samuelson L.C., and Meisler M.H., Genes Dev 6, 1457–1465, 1992.

    PubMed  CAS  Google Scholar 

  208. Stavenhagen J.B. and Robins D.M., Cell 55, 247–254, 1988.

    PubMed  CAS  Google Scholar 

  209. Jankowski J.M., States J.C., and Dixon G.H., J Mol Evol 23, 1–10, 1986.

    PubMed  CAS  Google Scholar 

  210. Corees V.G. and Geyer P.K., Trends Genet 7, 86–90, 1991.

    Google Scholar 

  211. White S.E., Habera L.F., and Wessler S.R., Proc Natl Acad Sci USA 91, 11792–11796, 1994.

    PubMed  CAS  Google Scholar 

  212. He X.-P., Bataillé N., and Fried H.M., J Cell Sci 107, 903–912, 1994.

    PubMed  CAS  Google Scholar 

  213. Hull M.W., Erickson J., Johnston M., and Engelke D.R., Mol Cell Biol 14, 1266–1277, 1994.

    PubMed  CAS  Google Scholar 

  214. Clemens M.J., Cell 49, 157–158, 1987.

    PubMed  CAS  Google Scholar 

  215. Vidal F. and Cuzin F., in Maraia R. (ed). The Impact of Short Interspersed Elements (SINEs) on the Host Genome. R.G. Landes, Austin, TX, 1995, pp. 125–131.

    Google Scholar 

  216. Smit A.F.A. and Riggs A.D., Nucleic Acids Res 23, 98–102, 1995.

    PubMed  CAS  Google Scholar 

  217. Jurka J., Zietkiewicz, and Labuda D., Nucleic Acids Res 23, 170–175, 1995.

    PubMed  CAS  Google Scholar 

  218. Murnane J.P. and Morales J.F., Nucleic Acids Res 23, 2837–2839, 1995.

    PubMed  CAS  Google Scholar 

  219. Tomilin N.V. and Bozhkov V.M., FEBS Lett 251, 79–83, 1989.

    PubMed  CAS  Google Scholar 

  220. Tomilin N.V., Iguchi-Ariga S.M.M., and Ariga H., FEBS Lett 263, 69–72, 1990.

    PubMed  CAS  Google Scholar 

  221. Gambari R., Volina S., Nesti C, Scapoli C, and Barra I., CABIOS 10, 501–508, 1994.

    PubMed  CAS  Google Scholar 

  222. Pesce CG., Rossi M.S., Muro A.F., Reig O.A., Zorzópoulos J., and Kornblith A.R., Nucleic Acids Res 22, 656–661, 1994.

    PubMed  CAS  Google Scholar 

  223. Boyko V., Mudrak O., Svetlova M., Negishi Y., Ariga H., and Tomilin N., FEBS Lett 345, 139–142, 1994.

    PubMed  CAS  Google Scholar 

  224. Schäfer U., Rausch O., Bouwmeester T., and Pieler T., Eur J Biochem 226, 567–576, 1994.

    PubMed  Google Scholar 

  225. Vansant G. and Reynolds W., Proc Natl Acad Sci USA 92, 8229–8233, 1995.

    PubMed  CAS  Google Scholar 

  226. Zierler M., Christy R.J., and Huang R.C.C., J Biol Chem 267, 21200–21206, 1992.

    PubMed  CAS  Google Scholar 

  227. Cho K.-O., Minsk B., and Wagner J.A., Proc Natl Acad Sci USA 87, 3778–3782, 1990.

    PubMed  CAS  Google Scholar 

  228. Kermekchiev M., Pettersson M., Matthias P., and Schaffner W., Gene Expr 1, 71–81, 1991.

    PubMed  CAS  Google Scholar 

  229. Sutcliffe J.G., Milner R.J., Gottesfeld J.M., and Reynolds W., Science 225, 1308–1315, 1984.

    PubMed  CAS  Google Scholar 

  230. Elredge N. and Gould S.J., in Schopf T.J.M. (ed). Models in Paleobiology. Freeman, Cooper, San Francisco, 1972, pp. 82–115.

    Google Scholar 

  231. Gould S.J. and Elredge N., Nature 366, 223–227, 1993.

    PubMed  CAS  Google Scholar 

  232. Paulson K.E., Matera A.G., Deka N., and Schmid C.W., Nucleic Acids Res 13, 5199–5215, 1987.

    Google Scholar 

  233. Banville D. and Boie Y., J Mol Biol 207, 481–490, 1989.

    PubMed  CAS  Google Scholar 

  234. Chang-Yeh A., Mold D.E., and Huang R.C.C., Nucleic Acids Res 19, 3667–3672, 1991.

    PubMed  CAS  Google Scholar 

  235. Feuchter A.E., Freeman J.D., and Mager D.L., Genomics 13, 1237–1246, 1992.

    PubMed  CAS  Google Scholar 

  236. Goodchild N.L., Wilkinson D.A., and Mager D.L., Gene 121, 287–294, 1992.

    PubMed  CAS  Google Scholar 

  237. Mager D.L., Virology 173, 591–599, 1989.

    PubMed  CAS  Google Scholar 

  238. Feuchter-Murthy A.E., Freeman J.D., and Mager D.L., Nucleic Acids Res 21, 135–143, 1993.

    PubMed  CAS  Google Scholar 

  239. Liu A.Y. and Abraham B.A., Cancer Res 51, 4107–4110, 1991.

    PubMed  CAS  Google Scholar 

  240. Baumruker T., Gehe C., and Horak I., Nucleic Acids Res 16, 7241–7251, 1988.

    PubMed  CAS  Google Scholar 

  241. Matsumine H., Herbst M.A., Ou S.-H.L, Wilson J.D., and McPhaul M.J., J Biol Chem 266, 19900–19907, 1991.

    PubMed  CAS  Google Scholar 

  242. Baniahmad A., Muller M., Steiner C, and Renkawitz R., EMBO J 6, 2297–2303, 1987.

    PubMed  CAS  Google Scholar 

  243. Harendza C.J. and Johnson L.F., Proc Natl Acad Sci USA 87, 2531–2535, 1990.

    PubMed  CAS  Google Scholar 

  244. Laimins L., Holmgren-König M., and Khoury G., Proc Natl Acad Sci USA 83, 3151–3155, 1986.

    PubMed  CAS  Google Scholar 

  245. Pérez M.J., Leroux C, Bonastre A.S., and Martin P., Gene 147, 179–187, 1994.

    PubMed  Google Scholar 

  246. Banki K., Halladay D., and Perl A., J Biol Chem 269, 2847–2851, 1994.

    PubMed  CAS  Google Scholar 

  247. Keshet E., Schiff R., and Itin A., Adv Cancer Res 56, 215–251, 1990.

    Google Scholar 

  248. Lewin R., Science 240, 603, 1988.

    PubMed  CAS  Google Scholar 

  249. Temin H.M., J Natl Cancer Inst 46, iii-vii, 1971.

    CAS  Google Scholar 

  250. Robertson N.G., Pomponio R.J., Mutter G.L., and Morton C.C., Nucleic Acids Res 19, 3129–3137, 1991.

    PubMed  CAS  Google Scholar 

  251. Deragon J.-M., Landry B.S., Pélissier T., Tutois S., Tourmente S., and Picard G., J Mol Evol 39, 378–386, 1994.

    PubMed  CAS  Google Scholar 

  252. McDonald J.F., Trends Ecol Evol 10, 123–126, 1995.

    PubMed  CAS  Google Scholar 

  253. Chesnokov I.N. and Schmid C.W., J Biol Chem 270, 18539–18542, 1995.

    PubMed  CAS  Google Scholar 

  254. Kaplan F.S., Murray J., Sylvester J.E., Gonzales I.L., O’Connor J.P., Doering J.L., Muenke M., Emanuel B.S., and Zasloff M.A., Genomics 15, 123–132, 1993.

    PubMed  CAS  Google Scholar 

  255. Rubin CM., VandeVoort C.A., Teplitz R.L., and Schmid C.W., Nucleic Acids Res 22, 5121–5127, 1994.

    PubMed  CAS  Google Scholar 

  256. Liu W.-M., Chu W.-M., Choudary P.V., and Schmid C.W., Nucleic Acids Res 23, 1758–1765, 1995.

    PubMed  CAS  Google Scholar 

  257. Goldschmidt R., The Material Basis of Evolution, Yale University Press, New Haven, CT, 1940.

    Google Scholar 

  258. Harris J.R., FEBS Lett 295, 3–4, 1991.

    PubMed  CAS  Google Scholar 

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  1. Jürgen Brosius

    Present address: Institute for Experimental Pathology, ZMBE University of Münster, Von-Esmarch Str. 56, Münster, D-48149, Germany

Authors and Affiliations

  1. Department of Pharmacology, Health Science Center at Brooklyn, State University of New York, Brooklyn, NY, USA

    Henri Tiedge

  2. Department of Neurology, Health Science Center at Brooklyn, State University of New York, Brooklyn, NY, USA

    Henri Tiedge

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  1. Jürgen Brosius
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  1. Department of Molecular Virology, The Hebrew University, Hadassah Medical School, Jerusalem, Israel

    Yechiel Becker

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Brosius, J., Tiedge, H. (1996). Reverse Transcriptase: Mediator of Genomic Plasticity. In: Becker, Y. (eds) Molecular Evolution of Viruses — Past and Present. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1407-3_8

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