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Causes and Control of Colorectal Cancer pp 47–68Cite as

Heredity

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Part of the book series: Developments in Oncology ((DION,volume 78))

Abstract

The inherited aspects of ordinary (sporadic) colorectal adenomas and ordinary (sporadic) colorectal cancer, familial adenomatous polyposis syndromes (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), will be discussed in this chapter. About 95% of all colorectal cancers are in the category of “ordinary” colorectal cancers, and FAP and HNPCC form about 5%. Those with a family history of colorectal cancer are known to be at a higher risk of developing this cancer than those who do not have a family history, and this has been assumed to be the main evidence for an inherited susceptibility to colorectal cancer.

A geneticist with a sense of humour was once asked whether insanity is inherited, and she replied, “Yes, you get it from your children!”

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Authors and Affiliations

  1. University of Melbourne, Australia

    Gabriel A. Kune MD FRACS FRCS FACS (Professor of Surgery Emeritus, Principal Investigator)

  2. Melbourne Colorectal Cancer Study, Australia

    Gabriel A. Kune MD FRACS FRCS FACS (Professor of Surgery Emeritus, Principal Investigator)

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  1. Gabriel A. Kune MD FRACS FRCS FACS
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© 1996 Kluwer Academic Publishers

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Kune, G.A. (1996). Heredity. In: Causes and Control of Colorectal Cancer. Developments in Oncology, vol 78. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1273-4_5

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  • DOI: https://doi.org/10.1007/978-1-4613-1273-4_5

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