Bowel Habit — Constipation, Diarrhea and Laxative Use

  • Gabriel A. Kune
Part of the Developments in Oncology book series (DION, volume 78)


It has been suggested that slow intestinal transit of feces through the large bowel is a risk for colorectal cancer. Slow intestinal transit may lead to constipation, however defined, so that constipation may be a marker for elevated colorectal cancer risk. At the other end of the bowel habit spectrum, it has been suggested that intestinal hurry, whatever the cause, and this may include laxative use, may have an irritant action on the mucosa of the large bowel, resulting in hyperplasia, dysplasia and neoplasia. It is known that in chronic ulcerative colitis and in chronic Crohn’s colitis, the risk of colorectal cancer is increased, but whether this is in part due to the associated chronic diarrhea, or mainly to other factors, is not known.


Colorectal Cancer Chronic Constipation Bowel Habit Chronic Ulcerative Colitis Colorectal Cancer Risk 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Kluwer Academic Publishers 1996

Authors and Affiliations

  • Gabriel A. Kune
    • 1
    • 2
  1. 1.University of MelbourneAustralia
  2. 2.Melbourne Colorectal Cancer StudyAustralia

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