Effects of vanadate on the expression of genes involved in fuel homeostasis in animal models of Type I and Type II diabetes

  • S. M. Brichard
Part of the Developments in Molecular and Cellular Biochemistry book series (DMCB, volume 16)


Vanadium is a trace element that has raised increasing interest in diabetology since the discovery of its insulin-like properties in vitro and in vivo. This brief article reviews the most recent data concerning the beneficial effects of vanadium compounds on fuel homeostasis in animal models of insulinopenic (Type I) or insulin-resistant (Type II) diabetes. These studies open obvious therapeutic possibilities in diabetes, and more particularly, in states of insulin resistance.

Key words

vanadium compounds insulin-dependent diabetes insulin-independent diabetes gene expression in liver 


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Copyright information

© Kluwer Academic Publishers 1995

Authors and Affiliations

  • S. M. Brichard
    • 1
  1. 1.Unité d’Endocrinologie et MétabolismeUniversity of Louvain, Faculty of Medicine, UCL 55.30BrusselsBelgium

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