Abstract
Over the past four years we have made a variety of immunotoxins (ITs) by coupling Pseudomonas exotoxin (PE), to monoclonal antibodies (MoAbs). Here the properties of PE, how it has been used to make (ITs), and the cell-killing activity of PE ITs are discussed and the potency of ITs made using other toxins are compared. Finally, prospects for the future use of this toxin are discussed.
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FitzGerald, D.J., Willingham, M.C., Pastan, I. (1988). Pseudomonas exotoxin — Immunotoxins. In: Frankel, A.E. (eds) Immunotoxins. Cancer Treatment and Research, vol 37. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1083-9_11
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DOI: https://doi.org/10.1007/978-1-4613-1083-9_11
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