Abstract
Characteristical feature of patients ith acute renal failure is a negative nitrogen balance with often dramatic wasting of skeletal muscle (1). In any major catabolic event, it is likely, that skeletal muscle provides an increased supply of amino acids for the enhanced metabolic activity of the liver. This loss of tissue may represent an adaptive response helping to meet the metabolic needs of the stressed organism. On the other hand, this loss of protein stores is probably a major contributing factor of the persistantly high mortality in patients with hypercatabolic acute renal failure.
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© 1988 Plenum Press, New York
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Schaefer, R.M., Teschner, M., Peter, G., Leibold, J., Kulzer, P., Heidland, A. (1988). Evidence for the Role of Proteinases in Uremic Catabolism. In: Hörl, W.H., Heidland, A. (eds) Proteases II. Advances in Experimental Medicine and Biology, vol 240. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1057-0_38
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DOI: https://doi.org/10.1007/978-1-4613-1057-0_38
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