Abstract
Among human chymotrypsin-like proteases, cathepsin G originates from leukocytes and up to now, its pathological role has not yet been elucidated even if it might be implicated in lung destruction during emphysema (Boudier et al., 1984) ; however, it is involved in all inflammatory processes. In an other hand, chymotrypsin A and pancreatic elastase 2 are secreted by pancreas and released in the circulation during acute pancreatic diseases. The proteolytic activity of these enzymes is regulated by the inhibitory capacity of some proteins. In the serum, α1-proteinase inhibitor (α1.PI) and α1-antichymotrypsin (α1.Achy) are the main serine-protease inhibitors, both of them being able to inhibit chymotrypsin-1ike proteases.
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© 1988 Plenum Press, New York
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Hayem, A., Marko, D., Laine, A., Davril, M. (1988). Inhibition of Human Chymotrypsin-Like Proteases by (α1-Proteinase Inhibitor and α1-Antichymotrypsin. In: Hörl, W.H., Heidland, A. (eds) Proteases II. Advances in Experimental Medicine and Biology, vol 240. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1057-0_11
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DOI: https://doi.org/10.1007/978-1-4613-1057-0_11
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