Sealing of Human Tubular Tissues with High Alkyl Cyanoacrylate Adhesive XKM-2 and Its Effects--A New Sterilization and Nonsurgical Technique
Sealing of human tubular tissues, such as oviduct, with adhesives has a good developing prospect for human birth control and treatments of some diseases. This paper discusses an ideal adhesive for sealing tubular tissues, explores operation methods of sealing, investigates the interaction of solidifed adhesive with the inside tube wall and evaluates clinical effects of sealing. The operation procedure is to first insert XKM-2 with a special appliance into the narrow part of the oviduct. After its inside wall is sealed, a bacteria-free inflammation appears there, then a foreign-matter granulation tumor is formed, finally the tube cavity is sealed by the proliferous fibre structure together with XKM-2 polymer for a long time. The curative success rate of sterilization is up to 95%. The longest time for sealing has been 15 years. Besides, sealing of pancreatic duct with XKM-2 has obtained satisfactory results as well.
KeywordsToxicity Epoxy Rubber Perforation Polyurethane
Unable to display preview. Download preview PDF.
- 1.R.H. Davis, J.M. Donald, G.K. Facog, H.B. Facog, “Effect on Fertility of Introuterotubal Injection of Gelation, ” Obst and Gynec, 4(3) 446, 1973.Google Scholar
- 2.J.A. Zipper, Ennio Stachetti, Mario Medel, “Human Fertility Control by Transvaginal Application of Quinacrine on the Fallopian Tube,” Fertil. and Steril., 21(8), 1970.Google Scholar
- 3.R.H. Richard, “Female Sterilization by Electrocoagulation of Tubal Ostia Using Hysteroscopy,” Am. J. Obst and Gynec, 117(6), 801, 1973.Google Scholar
- 4.J.F. Hulka, K.F. Omran, “Sterilization by Cryosurgery: A Report of Animal Fertility Studies, ” Fertil. and Steril., 22(2), 170, 1971.Google Scholar
- 5.Wang Ting-rui, Reproduction and Contraception, 1(3), 48, 1981.Google Scholar
- 6.Q Zhao-yin, R Chuan-liang,“Occlusive Procedure of Pancreatic Duct for Pancreaticoduodenectomy,” Chin. J. Sur. 23, 727, 1985.Google Scholar