Abstract
Chromosomes have occupied a pivotal position in genetics ever since their involvement in heredity became firmly established in the early years of the twentieth century. There has consequently been a longstanding and fervent desire to understand how chromosomes are organized, and in particular, to ascertain how the hereditary material is arranged and regulated at the molecular level.
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References
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Burkholder, G.D. (1988). The Analysis of Chromosome Organization by Experimental Manipulation. In: Gustafson, J.P., Appels, R. (eds) Chromosome Structure and Function. Stadler Genetics Symposia Series. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1037-2_1
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