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Effect of Fish Oil Feeding on Rat Heart Lipids : Composition and Ultramicroscopic Study

  • Gilles Nalbone
  • Jeannie Léonardi
  • Elise Termine
  • Henri Portugal
  • Paulette Lechêne
  • Huguette Lafont
Conference paper
Part of the NATO ASI Series book series (NSSA, volume 150)

Abstract

Long chain polyeneoic fatty acids (PUFA) have received large attention because of their beneficial effect on the cardiovascular system1. Among these fatty acids those of the n-3 family, largely represented in fish oils, were demonstrated to be more efficient in lowering plasma triglyceride and cholesterol levels than were the PUFA originating from vegetable oils2-7. Although fish oils may bring interesting approaches to prevent or treat atherosclerosis, they may however, adversely affect some vital functions like spleen prostaglandin production”, or give accumulation of degradative products of peroxydized lipids in tissues9-11. Few investigations have been devoted to the effect of fish oils feeding on heart lipid metabolism12, 13. In our comparative study rats were fed a salmon oil enriched diet for two months others a corn oil-enriched diet and the last group a low fat diet. Hearts lipids were analyzed and possible high fat-induced lipid accumulation in tissue was investigated by ultramicroscopic examination of ventricles.

Keywords

Unsaturation Index Heart Lipid Lower Plasma Triglyceride Peroxydized Lipid Ultramicroscopic Examination 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Gilles Nalbone
    • 1
  • Jeannie Léonardi
    • 1
  • Elise Termine
    • 1
  • Henri Portugal
    • 1
  • Paulette Lechêne
    • 1
  • Huguette Lafont
    • 1
  1. 1.INSERM Unité 130MarseilleFrance

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