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Changes in Vascular Regulation after Implantation of a Total Artificial Heart

  • Jaromir Vašků
  • M. Dostál
  • Jan Vašků
  • S. Doležel

Abstract

After resection of biological ventricles, and after implantation of artificial ventricles, the mechanisms of vascular regulation are markedly changed. This situation has been observed in 42 long-term experiments on calves and 1 experiment on a goat. In our research centre we have elaborated a functional concept of the causes of changes in the vascular capacitance area in long surviving animals and we have started to influence the state of increase of central venous pressure (CVP) in these animals according to this concept. We have attained positive results, and we hope that our contribution to the explanation of the CVP increase can help to keep the CVP within acceptable limits in long-term survivors with a total artificial heart.

Keywords

Central Venous Pressure Atrial Wall Vascular Regulation Liver Index Total Artificial Heart 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Jaromir Vašků
    • 1
    • 2
  • M. Dostál
    • 1
    • 2
  • Jan Vašků
    • 1
    • 2
  • S. Doležel
    • 1
    • 2
  1. 1.Institute of Pathological Physiology, Faculty of MedicineUniversity of J. E. PurkyneBrnoCzechoslovakia
  2. 2.Research Centre for Heart Support and Total Heart SubstitutionRegional Institute for National HealthBrnoCzechoslovakia

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