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Oxygen Activation by Neutrophils

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Oxygen Complexes and Oxygen Activation by Transition Metals

Abstract

Mobile, phagocytoeing cells were first observed in starfish larvae in 1882 by Elie Metchnikoff, who was subsequently able to demonstrate their central role in host defense against infection ln animals. In recognition of the significance of his discoveries, Metchnikoff was awarded the Nobel Prize in Physiology or Medicine in 1908. Since that time our understanding of the physiology and biochemistry of leukocytic cells has increased enormously; however, the microbicidal toxins produced by leukocytes and their disinfection mechanisms have remained poorly characterized, and are correspondingly the subject of increasing attention of medical researchers and biochemists.

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  1. Department of Chemical and Biological Sciences, Oregon Graduate Center, Beaverton, Oregon, USA

    James K. Hurst

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  1. Texas A&M University, College Station, Texas, USA

    Arthur E. Martell  & Donald T. Sawyer  & 

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Hurst, J.K. (1988). Oxygen Activation by Neutrophils. In: Martell, A.E., Sawyer, D.T. (eds) Oxygen Complexes and Oxygen Activation by Transition Metals. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0955-0_12

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