Charge Transport Across Lipid Bilayer Membranes: Lipophilic Ions, Ion Carriers and Channels
The interior of a lipid bilayer is a medium of low dielectric constant and therefore represents an extremely high energy barrier for the passage of small ions such as Na+ or K+. The ion permeability of biological membranes depends, to a large extent, on the presence of specialized membrane constituents which provide energetically favourable pathways for ion transport through the apolar core of the membrane. The following chapter deals with the study of such ion transport mechanisms (carrier and channel mechanisms) using artificial lipid bilayer membranes.
KeywordsBilayer Membrane Lipid Bilayer Membrane Dipolar Potential Interfacial Potential Planar Bilayer
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- T. HANAI, D.A. HAYDON and J. TAYLOR, Proc. Roy. Soc. Edinburgh Sect. A, 281, 377 (1964).Google Scholar
- YU. A. OVCHINNIKOV, V.T. IVANOV and A.M. SKROB, Membrane-active complexones, Elsevier Scientific Publishing Company, Amsterdam, (1974).Google Scholar
- E. BAMBERG, H. ALPES, H.–J. APELL, R. BENZ, K. JANKO, H. -A. KOLB, P. LAUGER and E. GROSS, FEBS Symposium No. 42, G. Semenza and E. Carafoli (Editors)), Springer Verlag, Berlin, (1977) pp. 179–201.Google Scholar
Further useful readings
- S. B. HLADKY and D. A. HAYDON, Current Topics in Membrane and Transport, 21, 327 (1984).Google Scholar