An Electrochemical Perspective on Excitable Membranes, Channels and Gating
The concepts and techniques of electrochemistry have much to offer in elucidating the properties of biological membranes. Their role has been particularly prominent in the study of excitation where the two subjects, electrochemistry and electrophysiology, had a common origin about 200 years ago in the dispute of Galvani and Volta over the origins of animal electricity. The current explanation of excitation, based on ideas of electrochemistry developed almost a century ago, will be presented here and the debt of biology to electrochemistry will be apparent.
KeywordsSurface Charge Density Outward Current Voltage Clamp Excitable Cell Interfacial Free Energy
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