The Effect of BW 755C on Wound Healing in a Scald Burn Injury Pig Model-Morphological and Biochemical Findings
The significance of the arachidonic acid metabolites as mediators of thermal lesions remains controversial (1,2,3). We have therefore examined the effect of BW 755C — a known inhibitor of cyclooxigenase and lipoxigenase-on wound healing. In this study 2 ndo scald burns effecting 20 % of the body surface of anesthetised pigs were induced (3). The effect of systemic administration of BW 755C (10 mg/kg/die)(n=7) five minutes following induction of the scald burn was compared with that of a control group (n=4).
KeywordsWound Healing Burned Area Biochemical Finding Arachidonic Acid Metabolite Improve Wound Healing
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