Importance of Immune Function in Trauma for Survival
Trauma may manifest itself in a number of different ways, including thermal injury, blunt injury, and the injury associated with elective surgery. Each of these forms of trauma has been demonstrated to produce important changes in the immune response which are clearly secondary and which in the absence of compounding variables such as the complications of infection, shock, malnutrition etc. have a recovery period which is a function of the magnitude of the injury and the age of the patient. This chapter will review data on the immune system following trauma and integrate these acquired immune defects with the increased likelihood of developing infection as well as the influence of compounding variables on the evolution of these defects.
KeywordsSkin Test Neutrophil Adherence Neutrophil Chemotaxis Donor Nephrectomy Blunt Injury
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