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Bioluminescence Assays Using Immobilized Enzymes in Bile Acid Analysis

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The Bile Acids: Chemistry, Physiology, and Metabolism

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Abstract

Although it is well established that serum bile concentrations are elevated in patients with various liver diseases [1, 2], the clinical utility of their determination is still debated. Two major, incompletely resolved problems limit the usefulness of such tests: (1) the exact definition of the principal physiological determinants of serum bile acid levels and pathological events affecting such concentrations, and (2) the analytical heterogeneity of the existing serum bile acid methods currently available.

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Author information

Authors and Affiliations

  1. Department of Internal Medicine, University of Freiburg, Freiburg, West Germany

    J. Schölmerich

  2. Institute of Chemical Sciences and Departments of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy

    A. Roda

  3. Department of Chemistry, University of California, San Diego, California, USA

    M. DeLuca

Authors
  1. J. Schölmerich
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  2. A. Roda
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  3. M. DeLuca
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Editor information

Editors and Affiliations

  1. Children’s Hospital Medical Center, Cincinnati, Ohio, USA

    Kenneth D. R. Setchell

  2. The Wistar Institute, Philadelphia, Pennsylvania, USA

    David Kritchevsky

  3. Lipid Nutrition Laboratory, Beltsville Human Nutrition Research Center, ARS, USDA, Beltsville, Maryland, USA

    Padmanabhan P. Nair

  4. The Johns Hopkins University School of Hygiene and Public Health, Baltimore, Maryland, USA

    Padmanabhan P. Nair

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© 1988 Plenum Press, New York

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Schölmerich, J., Roda, A., DeLuca, M. (1988). Bioluminescence Assays Using Immobilized Enzymes in Bile Acid Analysis. In: Setchell, K.D.R., Kritchevsky, D., Nair, P.P. (eds) The Bile Acids: Chemistry, Physiology, and Metabolism. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0901-7_7

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  • DOI: https://doi.org/10.1007/978-1-4613-0901-7_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8236-5

  • Online ISBN: 978-1-4613-0901-7

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