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The Glomerular Basement Membrane

A Selective Macromolecular Filter
  • Marilyn Gist Farquhar

Abstract

The basement membrane of the glomerular capillaries of the mammalian kidney has been a favorite object for studies on the structure, function, and composition of basement membranes because of its important biological role in glomerular filtration of macromolecules, and because of the relative ease with which it can be isolated for study, free from contamination by other extracellular matrix components. This chapter will review what is known about the characteristics of the glomerular basement membrane (hereafter abbreviated as GBM) and will compare wherever possible the available data with those on basement membranes from other sources.

Keywords

Basement Membrane Heparan Sulfate Mesangial Cell Glomerular Basement Membrane Anionic Site 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • Marilyn Gist Farquhar
    • 1
  1. 1.Section of Cell BiologyYale University School of MedicineNew HavenUSA

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