Carcinoma of the endometrium and hormonal receptors
Carcinoma of the endometrium is the most common gynecologic malignancy in the United States, accounting for 38,000 new cases and 3,200 deaths every year . Although surgery and radiation therapy are quite effective and achieve 80–90% cure rates in early stages, most of the fatalities occur in patients with advanced, recurrent, or metastatic disease.
KeywordsNude Mouse Endometrial Carcinoma Steroid Receptor Endometrial Adenocarcinoma Nude Mouse Model
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- 1.Silverberg E, 1982. Cancer statistics. CA 32:18–42.Google Scholar
- 3.Deppe E, 1984. Chemotherapy of endometrial carcinoma. In Chemotherapy of Gynecologic Cancer, (Deppe D, ed) New York: Alan R. Liss, pp. 139–150.Google Scholar
- 6.McGuire WL, Carbone PO, Vollmer EP, 1975. Estrogen Receptors in Human Breast Cancer. New York: Raven Press.Google Scholar
- 7.Allegra JC, Lippman ME, Thompson EB, Simon R, Bartock A, Green L, Hupp KK, Do HMI, Aitken SC, Warren R, 1978. Relationship between the progesterone, androgen, and glucocorticoid receptor and response rate to endocrine therapy in metastatic breast cancer. Cancer Treat Rep 62:1281–1286.PubMedGoogle Scholar
- 8.McGuire WL, 1978. Hormones, Receptors and Breast Cancer. New York: Raven Press.Google Scholar
- 9.Mortel R, Zaino RJ, Satyaswaroop PG, 1984. Sex steroid receptors and hormonal treatment of endometrial cancer. In Chemotherapy of Gynecologic Cancer, (Deppe G, ed). New York: Alan R Liss pp. 125–138.Google Scholar
- 10.Martin PM, Rolland PH, Gammere M, Serment H, Toga M, 1979. Estradiol and progesterone receptors in normal and neoplastic endometriums: Correlations between receptors, histopathological examinations and clinical responses under progestin therapy. Int J Cancer 24:324–329.Google Scholar
- 14.Martin PM, 1982. Endometrial cancer: Correlations between estrogen and progestin receptor status, histopathological findings, and clinical responses during progestin therapy. Excerpta Med Int Can Series 611:333–349.Google Scholar