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Premises for an Antioxidant Therapy in Pregnancy Induced Nephropathy

  • P. Stratta
  • C. Canavese
  • L. Gurioli
  • M. Porcu
  • M. Dogliani
  • F. Belliardo
  • E. Garbo
  • G. Artuffo
  • A. Vercellone
Part of the Developments in Nephrology book series (DINE, volume 24)

Abstract

Different experimental and clinical observations support an imbalance between oxidant and anti oxidant factors in preeclampsia (PE): a) an increased concentration of lipid peroxides, and byproducts of peroxidation due to free-radicals (1); b) a reduced ability to produce Prostacyclin by the fetal and maternal endothelial cells (2); c) the preeclamptic-like syndrome induced in pregnant rat by a vitamin E deficient diet (3); d) the directly reduced placental Prostacyclin production due to a deficit of Vitamin E (4).

Keywords

Uric Acid Serum Uric Acid Normal Pregnancy Total Serum Protein Plasma Vitamin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • P. Stratta
    • 1
  • C. Canavese
    • 1
  • L. Gurioli
    • 1
  • M. Porcu
    • 1
  • M. Dogliani
    • 1
  • F. Belliardo
    • 2
  • E. Garbo
    • 2
  • G. Artuffo
    • 2
  • A. Vercellone
    • 1
  1. 1.Department of NephrologyUniversity of TorinoItaly
  2. 2.Department of Science and Tecnology of DrugsUniversity of TorinoItaly

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