Criteria for Adequate Hemodialysis

  • Frank A. Gotch
Part of the Developments in Nephrology book series (DINE, volume 24)


The uremic syndrome results in multisystem organ failure which is only partly responsive to adequate dialysis. There is variable ongoing morbidity such as impaired appetite, mild sensory neuropathy, renal osteodystrophy and pruritis in well dialyzed patients and the mortality rate is strongly dependent on associated illnesses (1). Because of this variable ongoing clinical morbidity in these patients despite fully “adequate” dialysis it is very difficult if not impossible to reliably optimize the dose of dialysis from empirical observation of patient symptoms alone.


Renal Osteodystrophy Dialysis Therapy Adequate Dialysis Multisystem Organ Failure Clearance Pathway 
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  1. 1.
    Shapiro F, Umen A. Risk factors in hemodialysis patient survival. ASAIO Journal 6:176, 1983.Google Scholar
  2. 2.
    Gotch F. Kinetic Modeling in Hemodialysis, in Nissenson A and Gentile D, eds. Clinical Dialysis 2nd Ed. Appleton & Lange Publishers, in press, 1988.Google Scholar
  3. 3.
    Gotch F, Sargent J. A mechanistic analysis of the National Cooperative Dialysis Study (NCDS). Kidney Int. 28: 526, 1985.PubMedCrossRefGoogle Scholar

Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • Frank A. Gotch
    • 1
  1. 1.Hemodialysis Treatment and Research CenterDavies Medical CenterSan FranciscoUSA

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