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Oxalate Clearance by High Flux Haemodialysis Using Polyacrylonitrile Membranes

  • D Sethi
  • SH Morgan
  • P Purkiss
  • JR Curtis
  • Rwe Watts
Part of the Developments in Nephrology book series (DINE, volume 24)

Abstract

Hyperoxalaemia is of importance because it may cause significant morbidity and mortality due to the tissue deposition of calcium oxalate crystals. It has been most extensively studied in the primary hyperoxalurias but oxalate retention and raised serum levels also occur late in renal failure and hyperoxalaemia is well documented in patients on treatment with haemodialysis and continuous ambulatory peritoneal dialysis (CAPD). There have been no studies however on the clearance of oxalate in patients treated with high flux dialysers. We therefore measured the clearance of oxalate in 6 patients on treatment with polyacrylonitrile dialysers (AN69HF). This was compared to the oxalate clearance in 5 patients on treatment with cuprophane dialysers, reported in a previous study (1).

Keywords

High Flux Continuous Ambulatory Peritoneal Dialysis Calcium Oxalate Crystal Oxalate Oxidase Primary Hyperoxalurias 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Morgan, S.H., Maher, E.R., Purkiss, P., Watts, R.W.E., Curtis, J.R. Nephrol. Dial. Transplant. 3: 28–32, 1988.PubMedGoogle Scholar
  2. 2.
    Kasidas, G.P., Rose, G.A. Clin. Chim. Acta. 154: 49–58, 1986.PubMedCrossRefGoogle Scholar
  3. 3.
    Watts, R.W.E., Veall, N., Purkiss, P. Clin. Sci. 66: 591–597, 1984.PubMedGoogle Scholar

Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • D Sethi
    • 1
  • SH Morgan
    • 2
  • P Purkiss
    • 2
  • JR Curtis
    • 1
  • Rwe Watts
    • 2
  1. 1.Charing Cross Hospital LondonHarrowUK
  2. 2.MRC Clinical Research CentreHarrowUK

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