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Recent Advances in the Synthesis of Retinoids and Visual Pigment Analogs Studies

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Carotenoids

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Abstract

Recent activities in the field of synthetic retinoids have been stimulated by analog studies in the areas of cancer prevention using vitamin A and its derivatives,1 visual pigments2 and bacteriorhodopsin3 and other retinal containing proteins.4 It will not be possible to review here the variety of compounds available in the literature. Nor, will it be wise to repeat the effort of others who have already produced several extensive review articles.5 Instead, in this paper only efforts directed toward preparation of stereoisomers of vitamin A, a topic of interest here will be summarized.

Bioorganic Studies of Visual Pigments 10. For no. 9 in the series see ref. 2b. This work was supported by a grant from the U.S. Public Health Services (DK-17806).

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Authors and Affiliations

  1. Department of Chemistry, University of Hawaii, 2545 The Mall, Honolulu, Hawaii, 96822, USA

    Robert S. H. Liu, Taraneh Mirzadegan & Achla Trehan

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  1. Robert S. H. Liu
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  2. Taraneh Mirzadegan
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  3. Achla Trehan
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Editors and Affiliations

  1. Tufts University Health Sciences Campus, Boston, Massachusetts, USA

    Norman I. Krinsky

  2. Harvard Medical School, Boston, Massachusetts, USA

    Micheline M. Mathews-Roth

  3. Arthur D. Little, Inc., Cambridge, Massachusetts, USA

    Richard F. Taylor

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© 1989 Plenum Press, New York

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Liu, R.S.H., Mirzadegan, T., Trehan, A. (1989). Recent Advances in the Synthesis of Retinoids and Visual Pigment Analogs Studies. In: Krinsky, N.I., Mathews-Roth, M.M., Taylor, R.F. (eds) Carotenoids. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0849-2_8

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  • DOI: https://doi.org/10.1007/978-1-4613-0849-2_8

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  • Print ISBN: 978-1-4612-8113-9

  • Online ISBN: 978-1-4613-0849-2

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