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Evaluation of an In Vitro Dual Perfusion System for the Study of Placental Proteins: Energy Metabolism

  • H. Schneider
  • A. Malek
  • R. Duft
  • N. Bersinger

Abstract

The in vitro perfusion of human placenta offers several attractions to the investigator of placental function. Species differences which must be considered when data from animal experiments are discussed are of no concern and there are no ethical or safety questions. Furthermore the isolated in vitro situation allows the controlled modification of various experimental conditions. As in other in vitro techniques — for example, slices or membrane preparations — the tissue function is being studied after isolation from its natural environment, so considerable differences from in vitro behaviour are likely. Maternal and fetal influences which affect placental function by continuously modifying the “perfusate” are excluded, which is advantageous but at the same time present limitations in the interpretation of data.

Keywords

Vaginal Delivery Glucose Consumption Lactate Production Human Placenta Iodoacetic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • H. Schneider
    • 1
  • A. Malek
    • 1
  • R. Duft
    • 1
  • N. Bersinger
    • 2
  1. 1.University of BerneSwitzerland
  2. 2.University of ZurichSwitzerland

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