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Cell Function and Disease pp 405–413Cite as

Molecular Basis of Contrast in MRI

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Abstract

Water is an essential component as well as the most abundant molecule in all living systems. In magnetic resonance imaging (MRI) water is fundamental to image formation. Furthermore, the physical-chemical properties of cellular and extracellular water provide major contributions to the inherent contrast found in each image. The physical properties of water as a solvent are subject to change when macromolecular structure and/or motion is altered. Thus, precise knowledge of water-macromolecular interactions is required for our understanding of information content in an image obtained by magnetic resonance techniques.

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Author information

Authors and Affiliations

  1. Department of Physiology and Molecular Biophysics, Baylor College of Medicine, Houston, TX, 77030, USA

    T. F. Egan & C. F. Hazlewood

  2. Physics Department, Rice University, Houston, TX, 77251, USA

    H. E. Rorschach

Authors
  1. T. F. Egan
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  2. H. E. Rorschach
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  3. C. F. Hazlewood
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Editor information

Editors and Affiliations

  1. Department of Biochemistry School of Medicine, University of Nuevo Leon, Monterrey, Nuevo Leon, Mexico

    L. E. Cañedo

  2. Magnetic Resonance Unit, University Hospital, Monterrey, Nuevo Leon, Mexico

    L. E. Todd

  3. Lawrence Berkeley Laboratory, University of California, Berkeley, California, USA

    L. Packer

  4. International Biomedical Institute, Bari, Italy

    J. Jaz

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© 1988 Plenum Press, New York

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Egan, T.F., Rorschach, H.E., Hazlewood, C.F. (1988). Molecular Basis of Contrast in MRI. In: Cañedo, L.E., Todd, L.E., Packer, L., Jaz, J. (eds) Cell Function and Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0813-3_36

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  • DOI: https://doi.org/10.1007/978-1-4613-0813-3_36

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8095-8

  • Online ISBN: 978-1-4613-0813-3

  • eBook Packages: Springer Book Archive

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