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Investigation Of Metabolic Disorders in Patients and Animal Models Using Magnetic Resonance Spectroscopy

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Cell Function and Disease

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Abstract

This chapter will review the current status of in Vivo Magnetic Resonance Spectroscopy (MRS), with emphasis on the clinical applications of MRS. The results of MRS studies of muscle function, tumor metabolism, and other applications will be discussed. Techniques for obtaining MR signals from selected volumes of tissue and/or selected metabolites will be described.

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References

  1. R.K. Gupta, NMR Spectroscopy of Cells and Organisms, CRC Press, Boca Raton (1987)

    Google Scholar 

  2. H.P. Hetherington, M.J. Avison, R.G. Shulman, Proceedings of the National Academy of Sciences 82, 3115 (1985)

    Article  CAS  Google Scholar 

  3. K. Roth, B. Hubesch, S. Naruse, J. Gober, T. Lawry, M. Boska, G.B. Matson, and M.W. Weiner, (Abstract) Society of Magnetic Resonance in Medicine 2, 608 (1987)

    Google Scholar 

  4. D. Eidelberg, G. Johnson, D. Barnes, P.S. Tofts, D. Delpy, D. Plummer, and W.I. McDonald, Magnetic Resonance in Medicine 6, 244 (1988)

    Article  Google Scholar 

  5. R.T. Bogusky, M. Garwood, G.B. Matson, G. Acosta, L.D. Cowgill, and T. Schleich, Magnetic Resonance in Medicine 3, 251 (1986)

    Article  PubMed  CAS  Google Scholar 

  6. L.M. Schiffer, P.G. Braunschweiger, J.D. Glickson, W.T. Evanochko, T.C. Ng, Annals of the New York Academy of Science, 6481 (1981)

    Google Scholar 

  7. W.T. Evanochko, T.C. Ng, M.B. Lilly, A.J. Lawson, T.H. Corbelt, J.R. Durant, J.D. Glickson, Proc Natl Acad Sei USA 80, 334 (1983)

    Article  CAS  Google Scholar 

  8. J.R. Griffiths, A.N. Stevens, R.A. lies, R.E. Gordon, D. Shaw, Bioscience Reports 1, 319 (1981)

    Article  PubMed  CAS  Google Scholar 

  9. J.M. Maris, B. Chance, in Magnetic Resonance Annual, ed. Herbert Y. Kressel, Raven Press, New York, pp. 213 (1986)

    Google Scholar 

  10. N. Shine, M.A. Palladino, J.S. Patton, A. Deisseroth, G. Karczmar, G. Matson, and M.W. Weiner, Journal of Clinical Investigation, submitted

    Google Scholar 

  11. J.M. Arbeit, J.B. Toy, M.W. Weiner, (Abstract) Society of Magnetic Resonance in Medicine 1, 64 (1987)

    Google Scholar 

  12. G.S. Karczmar, M.W. Weiner, and G.B. Matson, Journal of Magnetic Resonance 71, 360 (1987)

    Google Scholar 

  13. G.S. Karczmar, T. Lawry, G.B. Matson, and M.W. Weiner, NMR in Biomedicine, submitted

    Google Scholar 

  14. G.S. Karczmar, J. Poole, Hubesch, K.Roth, G.B. Matson, Weiner, (Abstract) Society of in Medicine, submitted (1988)M.D. Boska, D.J. Meyerhoff, B. J. Arbeit, F. Valone, and M.W. Magnetic Resonance in Medicine

    Google Scholar 

  15. B. Hubesch, D. Sappey-Marinier, K. Roth, E. Sanuki, J.E. Hodes, G.B. Matson, and M.W. Weiner, ( Abstract) Society of Magnetic Resonance in Medicine, submitted (1988)

    Google Scholar 

  16. D.T. Twieg, D. Meyerhoff, J. Gober, M. Boska, B. Hubesch, S. Schaefer, K. Roth, D. Sappey-Marinier, and M.W. Weiner, ( Abstract) Society of Magnetic Resonance in Medicine, submitted (1988)

    Google Scholar 

  17. D.I. Hoult, S.J.W. Busby, D.G. Gadian, G.K. Radda, R.E. Richards, and P.J. Seeley, Nature 252, 285 (1974)

    Article  PubMed  CAS  Google Scholar 

  18. D.J. Taylor, P.J.Bore, P. Styles, D.G. Gadian, and G.K. Radda, Molecular Biology in Medicine 1, 77 (1983)

    CAS  Google Scholar 

  19. E.D. Ross, G.K. Radda, D.G. Gadian, G. Rocker, M. Esiri, and J. Falconer-Smith 304, 1338 (1981)

    Google Scholar 

  20. G.K. Radda, Science 233, 640 (1986)

    Article  PubMed  CAS  Google Scholar 

  21. G.K. Radda, Science 233, 640 (1986)

    Article  PubMed  CAS  Google Scholar 

  22. M.R. Boska, M. Moussavi, R. Miller, R. Layser, and M.W. Weiner, (Abstract) Society of Magnetic Resonance in Medicine 2, 446 (1986)

    Google Scholar 

  23. M.J. Dawson, K.J. Brooks, D. Mcfarlane, and S. J. Smith, (Abstract) Society of Magnetic Resonance in Medicine 2, 447 (1986)

    Google Scholar 

  24. W.E. Jacobus, G.J. Taylor, D.P. Hollis, and R.L. Nunnally, Nature 265, 756 (1977)

    Article  PubMed  CAS  Google Scholar 

  25. D.G. Gadian, D.I. Hoult, G.K. Radda, P.J. Seeley, B. Chance, and C. Barlow, Proceedings of the National Academy of Science USA 73, 4446 (1976)

    Article  CAS  Google Scholar 

  26. B.J. Toy, P. Lanzer, A. Camacho, M. Valenza, J. Gober, G.S. Karczmar, E. Botnivick, B. Massie, G.B. Matson, and M.W. Weiner, (Abstract) Society of Magnetic Resonance in Medicine 2, 1018 (1987)

    Google Scholar 

  27. P.A. Bottomley, R.J. Herfkens, L.S. Smith, S. Brazzamano, R. Blinder, L.W. Hedlund, J.L. Swain, and R.W. Redington, Proceedings of the National Academy of Science USA 82, 8747 (1985)

    Article  CAS  Google Scholar 

  28. M.J. Blackledge, B. Rajagopalan, R.D. Oberhansli, N.M. Bolas, P. Styles, and G.K. Radda, Proceedings of the National Academy of Science 84, 4283 (1987)

    Article  CAS  Google Scholar 

  29. R.J. Ordidge, A. Connelly, J.A.B. Lohman, J Magn Reson 66, 283 (1986)

    CAS  Google Scholar 

  30. R.J. Ordidge, A. Connelly, J.A.B. Lohman, J Magn Reson 66, 283 (1986)

    CAS  Google Scholar 

  31. B. Chance, Y. Nakase, M. Bond, J.S. Leigh Jr., and G. McDonald, Proceedings of the National Academy of Science USA 75, 4925 (1978)

    Article  CAS  Google Scholar 

  32. J.J.H. Ackerman, T.H. Grove, G.G. Wong, D.G. Gadian, and G.K. Radda, Nature 283, 167 (1980)

    Article  PubMed  CAS  Google Scholar 

  33. K.R. Thulborn, G. du Boulaym and G.K. Radda, Journal of Cerebral Blood Flow and Metabolism 1, 580 (1981)

    Google Scholar 

  34. J.W. Prichard and R.G. Shulman, Annual Review of Neurosciences 9, 61 (1986)

    Article  CAS  Google Scholar 

  35. D.J. Meyerhoff, G.B. Matson, G.S. Karczmar, M.D. Boska, D.R. Rockey, M.W. Weiner, Radiology, submitted

    Google Scholar 

  36. R.D. Oberhanslii, G.J. Galloway, D.J. Taylor, P.J. Bore, G.K. Radda, British Journal of Radiology 59, 695 (1986)

    Article  Google Scholar 

  37. M.D. Boska, D.B. Twieg, G.S. Karczmar, D.J. Meyerhoff, D. Sapey-Marinier, G.B. Matson, and M.W. Weiner (Abstract) Society of Magnetic Resonance in Medicine, submitted (1988)

    Google Scholar 

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Author information

Authors and Affiliations

  1. Magnetic Resonance Unit, Veterans Administration Medical Center and Depts. of Medicine and Radiology, University of California, San Francisco, USA

    Gregory S. Karczmar & Michael W. Weiner

Authors
  1. Gregory S. Karczmar
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  2. Michael W. Weiner
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Editor information

Editors and Affiliations

  1. Department of Biochemistry School of Medicine, University of Nuevo Leon, Monterrey, Nuevo Leon, Mexico

    L. E. Cañedo

  2. Magnetic Resonance Unit, University Hospital, Monterrey, Nuevo Leon, Mexico

    L. E. Todd

  3. Lawrence Berkeley Laboratory, University of California, Berkeley, California, USA

    L. Packer

  4. International Biomedical Institute, Bari, Italy

    J. Jaz

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© 1988 Plenum Press, New York

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Karczmar, G.S., Weiner, M.W. (1988). Investigation Of Metabolic Disorders in Patients and Animal Models Using Magnetic Resonance Spectroscopy. In: Cañedo, L.E., Todd, L.E., Packer, L., Jaz, J. (eds) Cell Function and Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0813-3_33

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  • DOI: https://doi.org/10.1007/978-1-4613-0813-3_33

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8095-8

  • Online ISBN: 978-1-4613-0813-3

  • eBook Packages: Springer Book Archive

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