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Pathophysiology of Diarrhea

Mechanisms of Action of Antidiarrheal Agents

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Book cover Modern Concepts in Gastroenterology Volume 2

Part of the book series: Topics in Gastroenterology ((TGEN))

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Abstract

It has been estimated that approximately 9 liters of fluid enters the gut each day: 1–1.5 liters from the diet; the rest as digestive secretions from the liver, pancreas, stomach, and small intestine. The majority of this fluid is absorbed during fairly rapid passage through the small intestine. About 1–1.5 liters passes through the ileocecal valve into the colon, and 90% of this is absorbed in the colon leaving the subject to pass a solid stool of approximately 100 g.

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  1. Sub-Department of Human Gastrointestinal Physiology and Nutrition, Royal Hal-lamshire Hospital, S10 2JF, Sheffield, UK

    N. W. Read

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  1. University of Calgary, Calgary, Alberta, Canada

    Eldon Shaffer M.D.

  2. The University of Alberta, Edmonton, Alberta, Canada

    Alan B. R. Thomson M.D., Ph.D.

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© 1989 Plenum Publishing Corporation

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Read, N.W. (1989). Pathophysiology of Diarrhea. In: Shaffer, E., Thomson, A.B.R. (eds) Modern Concepts in Gastroenterology Volume 2. Topics in Gastroenterology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0781-5_14

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  • DOI: https://doi.org/10.1007/978-1-4613-0781-5_14

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